Enriched Environment Attenuates Ferroptosis after Cerebral Ischemia/Reperfusion Injury via the HIF-1α-ACSL4 Pathway

Figure 2

Enriched environment attenuated neurological deficits caused by I/R injury. (a) Changes in mNSS for different groups on day 3, 7, and 21. Rats were trained preoperatively to avoid errors. (b) The escape latency in the spatial learning phase. (c, d) Time in the correct quadrant and the crossovers in the target quadrant was recorded and analyzed. (e) Representative swimming trajectories of SSC, SEE, ISC, and IEE groups in the probe trials. . Data are expressed as . and vs. SEE group; ^# and ^## vs. IEE group.

(a)

(b)

(c)

(d)

(e)