Curcumin Induces Ferroptosis in Follicular Thyroid Cancer by Upregulating HO-1 Expression

Figure 2

Transfection efficiency and growth inhibition rate. Transfection efficiencies of siHO-1 and HO-1-OE in Nthy-ori-3-1 and FTC cells (a–c). β-Actin was used as an internal control. (d–f) The growth inhibition rates of Nthy-ori-3-1 and FTC cells transfected with siHO-1 and treated with erastin (0, 1, 2, 4, 8, 16, and 32 μM). (g–i) The growth inhibition rates of Nthy-ori-3-1 and FTC cells transfected with HO-1-OE and treated with erastin (0, 1, 2, 4, 8, 16, and 32 μM). and compared with the Nc siRNA group. ^# and ^## compared with the vector group. The data are presented as the (SEM), . The test (a–c) and two-way ANOVA (d–i) were used to determine statistical significance.

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