Research Article

Inhibition of TRF2 Leads to Ferroptosis, Autophagic Death, and Apoptosis by Causing Telomere Dysfunction

Table 1

List of proteins in TRF2-p53-SLC7A11-GPX4 interaction network.

Abbreviation of geneFull name of gene

AURKAAurora kinase A
BARD1BRCA1-associated RING domain protein 1
CDK2Cyclin-dependent kinase 2
CREBBPCREB-binding protein
DDX5DEAD-box helicase 5
EP300E1A-binding protein P300
GPX4Glutathione peroxidase 4
MDM2MDM2 protooncogene
RPA1Replication protein A1
SIRT1NAD-dependent protein deacetylase sirtuin-1
SLC7A11Solute carrier family 7 (Xc-system), member 11
TERF2Telomeric repeat-binding factor 2
TP53Tumour protein P53
UBE3AUbiquitin-protein ligase E3A

The full names of genes are from the GeneCards database (http://www.genecards.org).