RING Finger Protein 10 Regulates AP-1/Meox2 to Mediate Pirarubicin-Induced Cardiomyocyte Apoptosis

Figure 1

THP causes general conditions and ECG abnormalities in rats. Compared with the ND group, THP resulted in a decrease in the (a) body weight and (b) food intake of rats. In addition, one rat in the THP group died every day on the 38th, 43rd, 44th, 48th, and 53rd days, while no death occurred in the ND group (c). (d) ECG showed that compared with the ND group, rats in the THP group had elevated (e) R waves, (f) S waves, and (g) T waves and (h) prolonged QT intervals. Values are expressed as the . (a, b) : two-way ANOVA; (c–h) : one-way ANOVA. , , , and vs. ND.

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