m6A Modification Mediates Endothelial Cell Responses to Oxidative Stress in Vascular Aging Induced by Low Fluid Shear Stress

Figure 1

Fluid shear stress dramatically regulates the m6A modifications on mRNA. (a) Schematic of the MeRIP sequencing analysis of HUVECs induced by fluid shear stress. The HUVECs were stimulated by fluid shear stress for 12 h. (b) Quantitation of the angles between long cell axis and flow direction. (c) Volcano plots of the hypermethylated and hypomethylated peaks regulated by different fluid shear stress.

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