Autophagy and Its Lineage-Specific Roles in the Hematopoietic System

Figure 3

Autophagy-related genes involved in hematopoietic differentiation. Schematic representation indicated that different autophagy and marker proteins play vital roles during hematopoiesis. Specific stages of hematopoietic cell differentiation require the putative mechanistic involvement of different autophagy genes as well as multiple autophagy factors. HSPC: hematopoietic stem and progenitor cell; CMP: common myeloid progenitor; CLP: common lymphoid progenitor; GMP: granulocyte-macrophage progenitor; NK: natural killer cell; PP: multipotent progenitor.