Oxidative Medicine and Cellular Longevity

Reactive Oxygen Species in Inflammation and Tissue Injury 2022


Publishing date
01 Dec 2022
Status
Closed
Submission deadline
12 Aug 2022

Lead Editor

1University of Science and Technology of China, Hefei, China

2Duke University, Durham, USA

3Central South University, Changsha, China

4Massachusetts Institute of Technology, Cambridge, USA

5University of California, San Francisco, USA

This issue is now closed for submissions.

Reactive Oxygen Species in Inflammation and Tissue Injury 2022

This issue is now closed for submissions.

Description

Reactive oxygen species (ROS) are classically defined as partially reduced oxygen derivatives that possess strong oxidizing capabilities. The concept of chronic or prolonged ROS production is considered central to the progression of inflammatory disease.

ROS produced by phagocytic cells are involved in the host-defense response and act as both signaling molecules and mediators of inflammation. The ambient levels of ROS are important for the homeostasis of cells, whereas excessive ROS are important in killing pathogens. Excessive ROS and insufficient antioxidants lead to inflammatory tissue injury. Thus, the antioxidant machinery of the cell plays an essential role in setting up this intricate balance. While it is clear that ROS are important to the pathogenesis of inflammation and tissue injury, much remains unknown about how ROS function physiologically and how they contribute to the mechanism of inflammation and tissue injury.

The aim of this Special Issue is to provide a broad and updated overview of the involvement of oxidative stress in inflammation and tissue injury. Knowledge on the interaction between oxidative stress and inflammation, and their role in tissue injury (e.g., ischemia-reperfusion injury, the stress of hyperoxia or high-glucose, atherosclerosis, toxins, neurodegenerative and metabolic hormonal disorders, etc.) will help develop strategies in combating these pathological conditions. Original research and review articles are welcome.

Potential topics include but are not limited to the following:

  • Sources and regulation of ROS in inflammation
  • Molecular mechanisms of oxidative stress-mediated signaling in inflammation
  • Interaction between ROS production and inflammatory responses
  • Oxidative stress and tissue injury
  • Roles of antioxidant therapy in inflammatory diseases and tissue injury
  • New insights into the relationship between oxidative stress and the immune system

Articles

  • Special Issue
  • - Volume 2022
  • - Article ID 2520348
  • - Research Article

Melatonin Suppresses Macrophage M1 Polarization and ROS-Mediated Pyroptosis via Activating ApoE/LDLR Pathway in Influenza A-Induced Acute Lung Injury

Meng-Meng Xu | Jia-Ying Kang | ... | Guang-He Fei
  • Special Issue
  • - Volume 2022
  • - Article ID 3281896
  • - Research Article

hucMSC-sEVs-Derived 14-3-3ζ Serves as a Bridge between YAP and Autophagy in Diabetic Kidney Disease

Siqi Yin | Wanzhu Liu | ... | Hui Qian
  • Special Issue
  • - Volume 2022
  • - Article ID 3458560
  • - Research Article

GSK 650394 Inhibits Osteoclasts Differentiation and Prevents Bone Loss via Promoting the Activities of Antioxidant Enzymes In Vitro and In Vivo

Lin-Yu Jin | Shi-Cheng Huo | ... | Xin-Feng Li
  • Special Issue
  • - Volume 2022
  • - Article ID 9018811
  • - Review Article

Liver Regeneration: Changes in Oxidative Stress, Immune System, Cytokines, and Epigenetic Modifications Associated with Aging

Chaoliang Tang | Hao Chen | ... | Lianxin Liu
  • Special Issue
  • - Volume 2022
  • - Article ID 2405943
  • - Research Article

Mucin 1 Inhibits Ferroptosis and Sensitizes Vitamin E to Alleviate Sepsis-Induced Acute Lung Injury through GSK3β/Keap1-Nrf2-GPX4 Pathway

Yu-Ming Wang | Fang-Chen Gong | ... | Er-Zhen Chen
  • Special Issue
  • - Volume 2022
  • - Article ID 7260305
  • - Research Article

The Combination of Rhodosin and MMF Prolongs Cardiac Allograft Survival by Inhibiting DC Maturation by Promoting Mitochondrial Fusion

Yanjia Che | Yuanyang Chen | ... | Xiaohan Zhong
  • Special Issue
  • - Volume 2022
  • - Article ID 2606928
  • - Review Article

Reactive Oxygen Species Bridge the Gap between Chronic Inflammation and Tumor Development

Weihua Yu | Yongmei Tu | ... | Chunxu Hai
  • Special Issue
  • - Volume 2022
  • - Article ID 8065771
  • - Research Article

Adipose Mesenchymal Stromal Cell-Derived Exosomes Prevent Testicular Torsion Injury via Activating PI3K/AKT and MAPK/ERK1/2 Pathways

Hengchen Liu | Manyu Shi | ... | Zhaozhu Li
  • Special Issue
  • - Volume 2022
  • - Article ID 6520789
  • - Research Article

miR-29a-3p in Exosomes from Heme Oxygenase-1 Modified Bone Marrow Mesenchymal Stem Cells Alleviates Steatotic Liver Ischemia-Reperfusion Injury in Rats by Suppressing Ferroptosis via Iron Responsive Element Binding Protein 2

Xiang Li | Longlong Wu | ... | Zhongyang Shen
  • Special Issue
  • - Volume 2022
  • - Article ID 2586305
  • - Research Article

Sitagliptin Alleviates Radiation-Induced Intestinal Injury by Activating NRF2-Antioxidant Axis, Mitigating NLRP3 Inf--lammasome Activation, and Reversing Gut Microbiota Disorder

Shanshan Huang | Yongbiao Huang | ... | Xianglin Yuan
Oxidative Medicine and Cellular Longevity
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Article of the Year Award: Outstanding research contributions of 2021, as selected by our Chief Editors. Read the winning articles.