Oxidative Medicine and Cellular Longevity

Using Reactive Oxygen and Nitrogen Species in Cancer Treatment


Publishing date
01 Feb 2020
Status
Closed
Submission deadline
27 Sep 2019

1Kwangwoon University, Seoul, Republic of Korea

2Leibniz Institute for Plasma Science and Technology (INP), Greifswald, Germany

3University of Bologna, Bologna, Italy

4King Saud University, Riyadh, Saudi Arabia

This issue is now closed for submissions.
More articles will be published in the near future.

Using Reactive Oxygen and Nitrogen Species in Cancer Treatment

This issue is now closed for submissions.
More articles will be published in the near future.

Description

In the past few years, the field of free radical chemistry has received a great deal of attention. Free radical reactive oxygen species (ROS) and reactive nitrogen species (RNS) are generated by our body through various endogenous systems, exposure to different physiochemical conditions, or pathological states. Reactive oxygen nitrogen species (RONS) are also produced as metabolic byproducts in numerous diseases. Generation of RONS within living cells is due to the mitochondrial electron transport system, NADH oxidase, and cytochrome P450, which all play a role in various crucial developmental processes, such as cell differentiation and cell signaling pathways. Recently, RONS have gained enormous attention due to their widespread application in the diverse fields of biology and medicine including cancer treatment, wound healing, sterilization of surfaces, blood coagulation, and dental as well as skin treatment. Oxidative stress, arising as a result of an imbalance between free radical production and antioxidant defenses, is associated with damage to a wide range of molecular species including lipids, proteins, and nucleic acids. In biological sciences free radicals or reactive species have the potential to revolutionize the treatment of diseases such as cancer.

The main aim of this special issue is to assemble the latest research on the potential biological application of RONS in cancer treatment. This includes research on RONS induced oxidative stress within biological systems and applications to help treat various cancers and improve metabolic activities and immune functions, leading to cellular survival and cellular longevity. We also welcome articles highlighting antioxidants that act as free radical scavengers in the intracellular and extracellular environment to lower ROS levels and relieve oxidative stress.

We invite authors to contribute original research articles as well as review articles exploring the role of RONS in cancer regulation.

Potential topics include but are not limited to the following:

  • The use of reactive oxygen species (ROS) and reactive nitrogen species (RNS) in cancer treatment
  • Cancer biology and treatment by using antioxidants
  • Oxidative stress and cancer
  • Cell survival and proliferation
  • Cancer biology and treatment
  • Dietary antioxidants and cancer prognosis
  • Immunomodulation and autophagy
  • Immunogenic cell death (ICD) and damage associated molecular patterns (DAMPs)
  • Redox status and metabolic circuits in cancer

Articles

  • Special Issue
  • - Volume 2020
  • - Article ID 2946820
  • - Research Article

Anticancer Activity of Liquid Treated with Microwave Plasma-Generated Gas through Macrophage Activation

Chae Bok Lee | Il Hwan Seo | ... | Ku Youn Baik
  • Special Issue
  • - Volume 2020
  • - Article ID 7240216
  • - Research Article

Hydroethanolic Extract of Solanum paniculatum L. Fruits Modulates ROS and Cytokine in Human Cell Lines

Ana Paula C. R. Ferraz | Alessandra Sussulini | ... | Camila R. Corrêa
  • Special Issue
  • - Volume 2020
  • - Article ID 5167292
  • - Research Article

The Phenoxyphenol Compound 4-HPPP Selectively Induces Antiproliferation Effects and Apoptosis in Human Lung Cancer Cells through Aneupolyploidization and ATR DNA Repair Signaling

Wangta Liu | Chang-Yi Wu | ... | Wen-Tsan Chang
  • Special Issue
  • - Volume 2020
  • - Article ID 7965435
  • - Research Article

Artichoke Polyphenols Sensitize Human Breast Cancer Cells to Chemotherapeutic Drugs via a ROS-Mediated Downregulation of Flap Endonuclease 1

Anna Maria Mileo | Donato Di Venere | ... | Stefania Miccadei
  • Special Issue
  • - Volume 2019
  • - Article ID 6346529
  • - Review Article

Spotlight on ROS and β3-Adrenoreceptors Fighting in Cancer Cells

Maura Calvani | Angela Subbiani | ... | Claudio Favre
  • Special Issue
  • - Volume 2019
  • - Article ID 6439021
  • - Research Article

Antitumoral and Immunomodulatory Effect of Mahonia aquifolium Extracts

Andra Diana Andreicuț | Eva Fischer-Fodor | ... | Alexandru Irimie
  • Special Issue
  • - Volume 2019
  • - Article ID 9474823
  • - Research Article

Mechanisms of Anthracycline-Enhanced Reactive Oxygen Metabolism in Tumor Cells

James H. Doroshow
  • Special Issue
  • - Volume 2019
  • - Article ID 9789241
  • - Research Article

Corn Silk (Zea mays L.) Induced Apoptosis in Human Breast Cancer (MCF-7) Cells via the ROS-Mediated Mitochondrial Pathway

Mai M. Al-Oqail | Ebtesam S. Al-Sheddi | ... | Maqsood A. Siddiqui
  • Special Issue
  • - Volume 2019
  • - Article ID 8535163
  • - Research Article

Elevated H2AX Phosphorylation Observed with kINPen Plasma Treatment Is Not Caused by ROS-Mediated DNA Damage but Is the Consequence of Apoptosis

Sander Bekeschus | Clarissa S. Schütz | ... | Matthias B. Stope
  • Special Issue
  • - Volume 2019
  • - Article ID 9240426
  • - Review Article

Targeting Reactive Oxygen Species in Cancer via Chinese Herbal Medicine

Qiaohong Qian | Wanqing Chen | ... | Jianchun Wu
Oxidative Medicine and Cellular Longevity
 Journal metrics
Acceptance rate44%
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Acceptance to publication39 days
CiteScore4.520
Impact Factor4.868
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