Oxidative Medicine and Cellular Longevity

Using Reactive Oxygen and Nitrogen Species in Cancer Treatment


Publishing date
01 Feb 2020
Status
Closed
Submission deadline
27 Sep 2019

1Kwangwoon University, Seoul, Republic of Korea

2Leibniz Institute for Plasma Science and Technology (INP), Greifswald, Germany

3University of Bologna, Bologna, Italy

4King Saud University, Riyadh, Saudi Arabia

This issue is now closed for submissions.
More articles will be published in the near future.

Using Reactive Oxygen and Nitrogen Species in Cancer Treatment

This issue is now closed for submissions.
More articles will be published in the near future.

Description

In the past few years, the field of free radical chemistry has received a great deal of attention. Free radical reactive oxygen species (ROS) and reactive nitrogen species (RNS) are generated by our body through various endogenous systems, exposure to different physiochemical conditions, or pathological states. Reactive oxygen nitrogen species (RONS) are also produced as metabolic byproducts in numerous diseases. Generation of RONS within living cells is due to the mitochondrial electron transport system, NADH oxidase, and cytochrome P450, which all play a role in various crucial developmental processes, such as cell differentiation and cell signaling pathways. Recently, RONS have gained enormous attention due to their widespread application in the diverse fields of biology and medicine including cancer treatment, wound healing, sterilization of surfaces, blood coagulation, and dental as well as skin treatment. Oxidative stress, arising as a result of an imbalance between free radical production and antioxidant defenses, is associated with damage to a wide range of molecular species including lipids, proteins, and nucleic acids. In biological sciences free radicals or reactive species have the potential to revolutionize the treatment of diseases such as cancer.

The main aim of this special issue is to assemble the latest research on the potential biological application of RONS in cancer treatment. This includes research on RONS induced oxidative stress within biological systems and applications to help treat various cancers and improve metabolic activities and immune functions, leading to cellular survival and cellular longevity. We also welcome articles highlighting antioxidants that act as free radical scavengers in the intracellular and extracellular environment to lower ROS levels and relieve oxidative stress.

We invite authors to contribute original research articles as well as review articles exploring the role of RONS in cancer regulation.

Potential topics include but are not limited to the following:

  • The use of reactive oxygen species (ROS) and reactive nitrogen species (RNS) in cancer treatment
  • Cancer biology and treatment by using antioxidants
  • Oxidative stress and cancer
  • Cell survival and proliferation
  • Cancer biology and treatment
  • Dietary antioxidants and cancer prognosis
  • Immunomodulation and autophagy
  • Immunogenic cell death (ICD) and damage associated molecular patterns (DAMPs)
  • Redox status and metabolic circuits in cancer

Articles

  • Special Issue
  • - Volume 2020
  • - Article ID 9490567
  • - Research Article

ZNRD1 and Its Antisense Long Noncoding RNA ZNRD1-AS1 Are Oppositely Regulated by Cold Atmospheric Plasma in Breast Cancer Cells

Hyeon Woo Kim | Dawoon Jeong | ... | Sun Jung Kim
  • Special Issue
  • - Volume 2020
  • - Article ID 1675613
  • - Research Article

IMCA Induces Ferroptosis Mediated by SLC7A11 through the AMPK/mTOR Pathway in Colorectal Cancer

Lei Zhang | Wen Liu | ... | Yanzhang Li
  • Special Issue
  • - Volume 2020
  • - Article ID 3985089
  • - Research Article

Fasting Induces Hepatocellular Carcinoma Cell Apoptosis by Inhibiting SET8 Expression

Jie Qi | Xiangyuan Chen | ... | Changhong Miao
  • Special Issue
  • - Volume 2020
  • - Article ID 7126976
  • - Research Article

Chidamide Inhibits Glioma Cells by Increasing Oxidative Stress via the miRNA-338-5p Regulation of Hedgehog Signaling

Haixia Zhou | Liang Han | ... | Zhaohui Li
  • Special Issue
  • - Volume 2020
  • - Article ID 4014838
  • - Research Article

Chemopreventive Effects of Propolis in the MNU-Induced Rat Mammary Tumor Model

A. F. Gal | L. Stan | ... | S. Andrei
  • Special Issue
  • - Volume 2020
  • - Article ID 2946820
  • - Research Article

Anticancer Activity of Liquid Treated with Microwave Plasma-Generated Gas through Macrophage Activation

Chae Bok Lee | Il Hwan Seo | ... | Ku Youn Baik
  • Special Issue
  • - Volume 2020
  • - Article ID 7240216
  • - Research Article

Hydroethanolic Extract of Solanum paniculatum L. Fruits Modulates ROS and Cytokine in Human Cell Lines

Ana Paula C. R. Ferraz | Alessandra Sussulini | ... | Camila R. Corrêa
  • Special Issue
  • - Volume 2020
  • - Article ID 5167292
  • - Research Article

The Phenoxyphenol Compound 4-HPPP Selectively Induces Antiproliferation Effects and Apoptosis in Human Lung Cancer Cells through Aneupolyploidization and ATR DNA Repair Signaling

Wangta Liu | Chang-Yi Wu | ... | Wen-Tsan Chang
  • Special Issue
  • - Volume 2020
  • - Article ID 7965435
  • - Research Article

Artichoke Polyphenols Sensitize Human Breast Cancer Cells to Chemotherapeutic Drugs via a ROS-Mediated Downregulation of Flap Endonuclease 1

Anna Maria Mileo | Donato Di Venere | ... | Stefania Miccadei
  • Special Issue
  • - Volume 2019
  • - Article ID 6346529
  • - Review Article

Spotlight on ROS and β3-Adrenoreceptors Fighting in Cancer Cells

Maura Calvani | Angela Subbiani | ... | Claudio Favre
Oxidative Medicine and Cellular Longevity
 Journal metrics
Acceptance rate48%
Submission to final decision56 days
Acceptance to publication37 days
CiteScore7.300
Impact Factor5.076
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