Oxidative Medicine and Cellular Longevity

From Oxidative Stress to Ageing via Lifestyle, Nutraceuticals, Polypharmacy, and Neuropsychological Factors


Publishing date
01 Aug 2018
Status
Published
Submission deadline
30 Mar 2018

Lead Editor

1Center for Food and Nutrition-Council for Agricultural Research and Economics (CREA-NUT), Rome, Italy

2University of Rome, Rome, Italy

3GITAM University, Visakhapatnam, India

4The University of Texas at San Antonio, San Antonio, USA

5King Abdulaziz University, Jeddah, Saudi Arabia


From Oxidative Stress to Ageing via Lifestyle, Nutraceuticals, Polypharmacy, and Neuropsychological Factors

Description

Lifestyle factors including dietary habit, physical activity, smoke, and physiological stress are modifiable determinants of the oxidative stress and the chronic low grade inflammation involved in the pathogenesis and progression of many ageing-associated diseases.

Ageing per se is associated with a decline in the antioxidant defenses, with telomere-shortening processes, with immunosenescence, with mitochondrial dysfunction, and with a higher susceptibility to ischemia/reperfusion and toxicants injuries. In particular, both cachexia and sarcopenic obesity are associated with impaired immune function and increased susceptibility to infection in aged frail people.

Although diet and exercise are the major players in the prevention of frailty in the elderly, moods can affect both the antioxidant defense and the immune system.

In addition to gender-related hormonal factors, socioeconomic status and moods influence nutritional status and physical activity in the elderly. On the other hand, physical activity and hedonic foods can improve moods. Therefore, there is a crosstalk between diet, genetic aspects, exercise, and mental health.

Controversies surrounding the usefulness of nutraceuticals in elderlies exist and possible food-drug interactions in aged people is an underlooked aspect of geriatric patients that could affect metabolic pathways.

Behavioral, epigenetic (dietary phytochemicals, drugs), and lifestyle (dietary intake, physical activity, and smoking habit) factors must be taken into account in the management of geriatric patients in order to assess individual risk or benefit of dietary and/or physical activity advice in the context of a personalized drug therapy.

In this special issue, we invite investigators to contribute original research articles based on both preclinical and clinical data, short or comprehensive reviews, and perspective articles aiming to evaluate the complex relationship between lifestyle, polypharmacy, and neuropsychological factors affecting oxidative stress-related diseases progression and management in the elderly.

Potential topics include but are not limited to the following:

  • Human or animal studies evaluating the effects of food, functional foods, nutraceuticals, and exercise on oxidative stress
  • Recent insights into the relationship between neuropsychological factors and oxidative stress
  • Molecular mechanisms of food-drug interaction, including genetic and epigenetic factors important in the area of geriatric polypharmacy
  • Recent studies on nongenetic or genetic influences that affect telomere attrition and possibly delay ageing-related diseases
  • New therapeutic interventions: immune, anti-inflammatory, and antioxidant aspects related to protection of accelerated ageing
  • Human evidence concerning the necessity of personalized nutrition and therapy in the elderly
  • Redox-modulated molecular pathways involved in aged-associated diseases (cancers, sarcopenia, osteopenia, immune-senescence, and metabolic, cardiovascular, and neurodegenerative diseases)

Articles

  • Special Issue
  • - Volume 2018
  • - Article ID 6352689
  • - Editorial

From Oxidative Stress to Ageing via Lifestyle, Nutraceuticals, Polypharmacy, and Neuropsychological Factors

Ilaria Peluso | Maura Palmery | ... | Mohammad A. Kamal
  • Special Issue
  • - Volume 2018
  • - Article ID 9286458
  • - Research Article

Melatonin Ameliorates the Progression of Atherosclerosis via Mitophagy Activation and NLRP3 Inflammasome Inhibition

Sai Ma | Jiangwei Chen | ... | Feng Cao
  • Special Issue
  • - Volume 2018
  • - Article ID 9395804
  • - Research Article

Antioxidant and Antisenescence Effects of Bergamot Juice

Eleonora Da Pozzo | Marinella De Leo | ... | Claudia Martini
  • Special Issue
  • - Volume 2018
  • - Article ID 8575263
  • - Review Article

The Effect of MitoQ on Aging-Related Biomarkers: A Systematic Review and Meta-Analysis

Andrea J. Braakhuis | Rohith Nagulan | Vaughan Somerville
  • Special Issue
  • - Volume 2018
  • - Article ID 2731289
  • - Research Article

Phenolic Plant Extracts Induce Sirt1 Activity and Increase Antioxidant Levels in the Rabbit’s Heart and Liver

G. Corbi | V. Conti | ... | D. Casamassima
  • Special Issue
  • - Volume 2018
  • - Article ID 4671213
  • - Research Article

The Electrical Stimulation of the Bed Nucleus of the Stria Terminalis Causes Oxidative Stress in Skeletal Muscle of Rats

Mateusz Jakub Karnia | Dorota Myslinska | ... | Jan Jacek Kaczor
  • Special Issue
  • - Volume 2018
  • - Article ID 4504079
  • - Research Article

A Pilot Study Providing Evidence for a Relationship between a Composite Lifestyle Score and Risk of Higher Carotid Intima-Media Thickness: Is There a Link to Oxidative Stress?

Neda Seyedsadjadi | Jade Berg | ... | Ross Grant
  • Special Issue
  • - Volume 2018
  • - Article ID 3090517
  • - Research Article

Synthesis, Characterization, and Biodistribution of Quantum Dot-Celecoxib Conjugate in Mouse Paw Edema Model

Suresh K. Kalangi | Nitin K. Swarnakar | ... | Pallu Reddanna
  • Special Issue
  • - Volume 2018
  • - Article ID 4147320
  • - Research Article

Long-Term Resveratrol Supplementation as a Secondary Prophylaxis for Stroke

Katalin Fodor | Delia Mirela Tit | ... | Simona Bungau
Oxidative Medicine and Cellular Longevity
 Journal metrics
Acceptance rate48%
Submission to final decision56 days
Acceptance to publication37 days
CiteScore7.300
Impact Factor5.076
 Submit

We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.