Oxidative Medicine and Cellular Longevity

Vascular Oxidative Stress: Pharmacological and Nonpharmacological Approaches


Status
Published

Lead Editor

1IRCCS Neuromed, Pozzilli, Italy

2University of Salerno, Fisciano, Italy


Vascular Oxidative Stress: Pharmacological and Nonpharmacological Approaches

Description

Compelling experimental evidence indicates that reactive oxygen species (ROS) play an important pathophysiological role in the development of cardiovascular diseases (CVDs). This is due, in large part, to .O2- excess and decreased NO bioavailability in the vasculature and to ROS-mediated cardiovascular remodelling. To date, although the common pharmacological therapy with statins, antihypertensives, and anti-inflammatory drugs has reduced over 50% of the mortality for cardiovascular events, their potential role as modulators of vascular oxidative stress is currently an area of active research. Moreover, although, in the last decade, accumulating evidence has highlighted the potential effects of the natural-derived compound to reduce the oxidative stress and to protect against the progression of cardiovascular diseases, the identification of the molecular mechanisms of intracellular signalling remains to be elucidated.

Based on these data, we invite investigators to contribute original research as well as review articles on the antioxidant vascular effects of different pharmacological and nonpharmacological approaches to prevent and fight the development of cardiovascular diseases.

We are focused on articles describing new mechanisms, new molecules, and new approaches to regulate oxidative stress in cardiovascular diseases.

Potential topics include but are not limited to the following:

  • In vitro and in vivo studies on the role of oxidative stress in endothelial dysfunction: pharmacological and nonpharmacological approaches
  • How ROS regulate signalling molecules in the cardiovascular system
  • Natural derived-compounds in controlling redox imbalance in the cardiovascular diseases
  • Characterization of mechanism of action of functional foods on cardiovascular diseases
  • Pharmacological and nonpharmacological approaches: what is the best way to decrease ROS bioavailability

Articles

  • Special Issue
  • - Volume 2018
  • - Article ID 8539350
  • - Editorial

Vascular Oxidative Stress: Pharmacological and Nonpharmacological Approaches

Valeria Conti | Maurizio Forte | Albino Carrizzo
  • Special Issue
  • - Volume 2018
  • - Article ID 4036709
  • - Research Article

Comparison of Pulmonary and Systemic NO- and PGI2-Dependent Endothelial Function in Diabetic Mice

Andrzej Fedorowicz | Elżbieta Buczek | ... | Stefan Chlopicki
  • Special Issue
  • - Volume 2018
  • - Article ID 5967890
  • - Research Article

BAG3 Protein Is Involved in Endothelial Cell Response to Phenethyl Isothiocyanate

Silvia Franceschelli | Anna Paola Bruno | ... | Maria Pascale
  • Special Issue
  • - Volume 2018
  • - Article ID 2568569
  • - Review Article

Vascular Endothelial Dysfunction in Inflammatory Bowel Diseases: Pharmacological and Nonpharmacological Targets

Antonietta Gerarda Gravina | Marcello Dallio | ... | Alessandro Federico
  • Special Issue
  • - Volume 2018
  • - Article ID 5879281
  • - Research Article

A Typical Immune T/B Subset Profile Characterizes Bicuspid Aortic Valve: In an Old Status?

Carmela R. Balistreri | Silvio Buffa | ... | Giacomo Frati
  • Special Issue
  • - Volume 2018
  • - Article ID 2609847
  • - Research Article

Formyl Peptide Receptor 1 Modulates Endothelial Cell Functions by NADPH Oxidase-Dependent VEGFR2 Transactivation

Fabio Cattaneo | Martina Castaldo | ... | Rosario Ammendola
  • Special Issue
  • - Volume 2018
  • - Article ID 4946289
  • - Review Article

Targeting the Endoplasmic Reticulum Unfolded Protein Response to Counteract the Oxidative Stress-Induced Endothelial Dysfunction

Giuseppina Amodio | Ornella Moltedo | ... | Paolo Remondelli
  • Special Issue
  • - Volume 2018
  • - Article ID 5942916
  • - Research Article

Transplantation of Bone Marrow Mesenchymal Stem Cells Prevents Radiation-Induced Artery Injury by Suppressing Oxidative Stress and Inflammation

Yanjun Shen | Xin Jiang | ... | Ying Xin
Oxidative Medicine and Cellular Longevity
 Journal metrics
Acceptance rate48%
Submission to final decision56 days
Acceptance to publication37 days
CiteScore7.300
Impact Factor5.076
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