Plants predate animals on earth, and their evolutionary adaptation has made them colonize almost all ecosystems on earth. Thus, the interaction between plants and humans is inevitable, and humans today use plants in many ways, namely as food, creams, lotions, drugs, aromas, and clothes.

Within the scientific community - and even beyond it – terms such as ‘antioxidant’, ‘prooxidant’, ‘oxidative stress’, ‘ROS’, and ‘RNS’ are well known and well-studied. Underlying these are complicated mechanisms that are triggered and inhibited at a molecular or cellular level, and these are not as well understood. Thus, further studies should be carried out to further understand these inner workings of oxidative stress, and how pathways are formed and influenced by outside phenomena.

The aim of this Special Issue is to present original research and review articles that focus on understanding the different manners in which plant compounds interact with human cells and the way oxidative stress, ROS, oxidative pathways, inflammation, and other reactions are influenced by them.

Potential topics include but are not limited to the following:

• Effect of plants, plant extracts, and plant derived substances towards oxidative stress
• Correlation between cellular and molecular oxidative pathways with plant compounds
• Effect of plant-based molecules towards known radicals and similar oxidative species
• Studies on redox signaling
• Effect of plant-based compounds on different radical producing cell organelles, such as mitochondria, endoplasmatic reticulum, peroxisomes, golgi apparatus, nucleusand plasma membrane
• Dichotomy between plant-based antioxidants and prooxidants