Oxidative Medicine and Cellular Longevity

Oxidative Stress in the Newborn


Status
Published

1University of Siena, Siena, Italy

2Service de Réanimation Pédiatrique et Néonatologie, Tours, France


Oxidative Stress in the Newborn

Description

Oxidative stress (OS) occurs when the production of prooxidant free radicals species exceeds the capacity of cells to neutralize or scavenge them. OS can be a risk factor for fetal programming, representing a key process linking adverse fetal growth, impaired fetal wellbeing, or preterm birth and later increased risks of diseases in adolescence and adulthood. Adverse outcome to the offspring can extend beyond the neonatal period and includes neurodevelopmental disorders (motor and cognitive problems, attention deficit hyperactivity, and psychotic disorders), asthma, insulin resistance, diabetes mellitus, hypertension, coronary heart disease, and stroke. Free radicals can alter gene expression or damage lipids, proteins, and DNA at a critical developmental point leading to a higher susceptibility to many disorders.

We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to understand the pathology underlying OS damage to the newborn, the development of strategies to treat or prevent OS-mediated diseases, and the evaluation of outcomes in this high-risk population.

We are particularly interested in articles describing the new modalities for clinical and biochemical characterization of OS damage and measuring outcomes from treatment trials, advances in molecular diagnostics, new insights into OS-mediated tissue damage using animal models, and current concepts in the prevention and treatment of oxidation using antioxidants, stem cells, and other protective strategies.

Potential topics include but are not limited to the following:

  • Recent developments in OS-mediated diseases in fetus and newborns
  • Advances in identification of prenatal and neonatal characteristics of the infant/foetus at increased risk of OS-mediated damage
  • Latest technologies for biochemical evaluation of OS in the fetus and newborn
  • Mechanisms of OS-mediated perinatal tissue damage using model systems
  • Recent advances in antioxidant drug delivery and follow-up studies to prevent neurodevelopmental impairment and to ameliorate outcome

Articles

  • Special Issue
  • - Volume 2017
  • - Article ID 1094247
  • - Editorial

Oxidative Stress in the Newborn

Giuseppe Buonocore | Serafina Perrone | Maria Luisa Tataranno
  • Special Issue
  • - Volume 2017
  • - Article ID 3759287
  • - Research Article

Oxidative Stress as a Physiological Pain Response in Full-Term Newborns

S. Perrone | C. V. Bellieni | ... | G. Buonocore
  • Special Issue
  • - Volume 2016
  • - Article ID 4569108
  • - Research Article

Cord Blood Adiponectin and Visfatin Concentrations in relation to Oxidative Stress Markers in Neonates Exposed and Nonexposed In Utero to Tobacco Smoke

Magdalena Chełchowska | Jadwiga Ambroszkiewicz | ... | Joanna Mazur
  • Special Issue
  • - Volume 2016
  • - Article ID 8651820
  • - Review Article

“Cumulative Stress”: The Effects of Maternal and Neonatal Oxidative Stress and Oxidative Stress-Inducible Genes on Programming of Atopy

Sara Manti | Lucia Marseglia | ... | Carmelo Salpietro
  • Special Issue
  • - Volume 2016
  • - Article ID 9247493
  • - Research Article

Erythropoietin Restores Long-Term Neurocognitive Function Involving Mechanisms of Neuronal Plasticity in a Model of Hyperoxia-Induced Preterm Brain Injury

Daniela Hoeber | Marco Sifringer | ... | Ivo Bendix
  • Special Issue
  • - Volume 2016
  • - Article ID 2768365
  • - Review Article

Oxidative Stress Related Diseases in Newborns

Yasemin Ozsurekci | Kubra Aykac
  • Special Issue
  • - Volume 2016
  • - Article ID 5763743
  • - Research Article

Immediate Remote Ischemic Postconditioning Reduces Brain Nitrotyrosine Formation in a Piglet Asphyxia Model

Eridan Rocha-Ferreira | Brogan Rudge | ... | Nicola J. Robertson
  • Special Issue
  • - Volume 2016
  • - Article ID 5057610
  • - Research Article

Oxidative Stress in the Developing Rat Brain due to Production of Reactive Oxygen and Nitrogen Species

Jiří Wilhelm | Richard Vytášek | ... | Luděk Vajner
  • Special Issue
  • - Volume 2016
  • - Article ID 1971452
  • - Review Article

Oxidative Stress after Surgery on the Immature Heart

Daniel Fudulu | Gianni Angelini
Oxidative Medicine and Cellular Longevity
 Journal metrics
Acceptance rate48%
Submission to final decision56 days
Acceptance to publication37 days
CiteScore7.300
Impact Factor5.076
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