Oxidative Medicine and Cellular Longevity

Molecular Mechanisms of Bioactive Compounds in Redox Balance and Metabolic Disease 2021


Publishing date
01 Feb 2022
Status
Closed
Submission deadline
08 Oct 2021

Lead Editor

1Hunan Agricultural University, Changsha, China

2Kagoshima University, Kagoshima, Japan

3University of Arizona, Tucson, USA

4Chongqing University Central Hospital, Chongqing, China

5Boston University, Boston, USA

6Mae Fah Luang University, Chiang Rai, Thailand

This issue is now closed for submissions.
More articles will be published in the near future.

Molecular Mechanisms of Bioactive Compounds in Redox Balance and Metabolic Disease 2021

This issue is now closed for submissions.
More articles will be published in the near future.

Description

Redox imbalance is one of the most prominent symptoms in patients suffering from metabolic diseases, often caused by an active inflammatory response or excess oxidative stress. The population of people with obesity and diabetes has increased rapidly all over the world. An increasing amount of scientific data is implying that dietary bioactive compounds, such as phytochemicals and nutraceuticals, can protect cells from excess oxidative/endoplasmic reticulum stress and ameliorate related diseases via regulating cell redox signaling pathways and changing gut microbiota. Meanwhile, many molecules are considered to perform vital bio-functions in repairing metabolic disorders caused by excess oxidative/endoplasmic reticulum stress. However, the detailed mechanisms underlying the role of these bioactive compounds in the regulation of inflammation, oxidative/endoplasmic reticulum stress, and the microbiome in chronic diseases remain largely unclear.

In this Special Issue, we invite distinguished investigators to contribute original research articles using in vitro or in vivo models, coupled with multi-omics tools or clinical studies, to address the roles of phytochemicals or other dietary bioactive compounds on the regulation of cell redox signaling and oxidative/endoplasmic reticulum stress according to organ/cell type, and further elucidate or reveal the molecular mechanisms underlying their actions, especially with the aid of multi-omics. Review articles are also welcomed.

Potential topics include but are not limited to the following:

  • The role of bioactive compounds in the development of oxidative/endoplasmic reticulum stress-related human diseases
  • The underlying mechanisms of the modulation of intestinal epithelia, gut microbiota, and oxidative/endoplasmic reticulum stress
  • The impact of dietary bioactive compounds on molecular, genetic, and biochemical biomarkers of oxidative/endoplasmic reticulum stress-related metabolic diseases
  • Multi-omics tools application in revealing the relationship between phytochemicals and human diseases
  • The regulation mechanism of bioactive compounds in diabetes, obesity and its complications
  • Development of nutritional strategies to reduce the risks caused by dietary bioactive compounds

Articles

  • Special Issue
  • - Volume 2022
  • - Article ID 3861380
  • - Research Article

Yaobishu Regulates Inflammatory, Metabolic, Autophagic, and Apoptosis Pathways to Attenuate Lumbar Disc Herniation

Xiaosheng Li | Shuoqi Li | ... | Yinhao He
  • Special Issue
  • - Volume 2022
  • - Article ID 3355687
  • - Research Article

Effects of Dietary Protein Level on the Microbial Composition and Metabolomic Profile in Postweaning Piglets

Jing Gao | ZeMin Liu | ... | TieJun Li
  • Special Issue
  • - Volume 2022
  • - Article ID 6316611
  • - Research Article

Effects of Dietary Chlorogenic Acid Supplementation Derived from Lonicera macranthoides Hand-Mazz on Growth Performance, Free Amino Acid Profile, and Muscle Protein Synthesis in a Finishing Pig Model

Wenlong Wang | Fengna Li | ... | Yulong Yin
  • Special Issue
  • - Volume 2022
  • - Article ID 1429869
  • - Review Article

The Role of Bioactive Compounds in Natural Products Extracted from Plants in Cancer Treatment and Their Mechanisms Related to Anticancer Effects

Meng Yuan | Guoqing Zhang | ... | Siman Bian
  • Special Issue
  • - Volume 2022
  • - Article ID 9965334
  • - Research Article

Transdermal Administration of Volatile Oil from Citrus aurantium-Rhizoma Atractylodis Macrocephalae Alleviates Constipation in Rats by Altering Host Metabolome and Intestinal Microbiota Composition

Liangfeng Wang | Fang Wang | ... | Ming Yang
  • Special Issue
  • - Volume 2022
  • - Article ID 9369035
  • - Research Article

lncRNA IGF2-AS Regulates Nucleotide Metabolism by Mediating HMGA1 to Promote Pyroptosis of Endothelial Progenitor Cells in Sepsis Patients

Guibin Liang | Menghao Zeng | ... | Zhihui He
  • Special Issue
  • - Volume 2021
  • - Article ID 7159652
  • - Research Article

Astaxanthin-Mediated Bacterial Lethality: Evidence from Oxidative Stress Contribution and Molecular Dynamics Simulation

Jamiu Olaseni Aribisala | Sonto Nkosi | ... | Saheed Sabiu
  • Special Issue
  • - Volume 2021
  • - Article ID 2713511
  • - Review Article

Lycopene: Food Sources, Biological Activities, and Human Health Benefits

Usman Mir Khan | Mustafa Sevindik | ... | Javad Sharifi-Rad
  • Special Issue
  • - Volume 2021
  • - Article ID 2796700
  • - Research Article

Antifungal Treatment Aggravates Sepsis through the Elimination of Intestinal Fungi

Baifa Sheng | Yihui Chen | ... | Hua Yang
  • Special Issue
  • - Volume 2021
  • - Article ID 4448048
  • - Research Article

Kudzu Resistant Starch: An Effective Regulator of Type 2 Diabetes Mellitus

Xinqi Song | Huanhuan Dong | ... | Yongmei Guan
Oxidative Medicine and Cellular Longevity
 Journal metrics
See full report
Acceptance rate33%
Submission to final decision83 days
Acceptance to publication26 days
CiteScore9.300
Journal Citation Indicator0.730
Impact Factor7.310
 Submit

Article of the Year Award: Outstanding research contributions of 2021, as selected by our Chief Editors. Read the winning articles.