Oxidative Medicine and Cellular Longevity

Plant-Derived Antioxidants in Disease Prevention


Status
Published

1AGH University of Science and Technology, Krakow, Poland

2Palacký University, Olomouc, Czech Republic

3Jagiellonian University, Krakow, Poland


Plant-Derived Antioxidants in Disease Prevention

Description

Oxidative stress is generated by an imbalance between reactive oxygen species (ROS) and antioxidants. An excess of ROS leads to the degradation of lipids, proteins, and DNA and thus may lead to oxidative damage to cells and, in consequence, to the overexpression of oncogenes, mutagen formation, the induction of atherogenic activity, or inflammation. Oxidative stress is thought to play a major role in the pathogenesis of cardiovascular diseases, neurodegeneration, cancer, immune disorders, diabetes, aging, and others. Plants, especially dietary fruits and vegetables, are a rich source of antioxidants. It is postulated that antioxidants produce health benefits through the direct reduction of oxidative stress. In the body, the antioxidant network works in concert through several different mechanisms: ROS scavenging, lipid peroxidation, and the inhibition or chelation of metals. However, our understanding of the specific role and mechanisms of the action of certain antioxidants is still in infancy. Many in vitro and in vivo studies indicate that a single antioxidant (i.e., -carotene and vitamin C or E) or diets rich in plant food provide protection against a set of diseases. However, several clinical trials on antioxidant action have produced contrasting results, with some showing a positive effect and others showing no evident results or even an increase in mortality.

We invite authors to submit original research as well as review articles that seek to understand the strategies and mechanisms of plant-derived antioxidants action in disease prevention. We are interested in articles that explore aspects of natural antioxidant action in humans and also in animal models. We are particularly interested in articles describing novel antioxidants, original approaches, and clinical studies on plant antioxidant involvement in disease prevention and treatment.

Potential topics include, but are not limited to:

  • Recent developments in plant-derived antioxidant research
  • Isolation and testing of novel and effective natural antioxidants
  • Role of plant-derived antioxidants in disease prevention
  • Identification of new, possible therapeutic mechanisms of antioxidant action
  • Latest strategies for clinical evaluation and measuring
  • Meta-analysis of randomized clinical trials to assess the beneficial or harmful effects of antioxidant supplements for disease prevention

Articles

  • Special Issue
  • - Volume 2020
  • - Article ID 8265810
  • - Retraction

Retracted: Protective Effects of Soy Oligopeptides in Ultraviolet B-Induced Acute Photodamage of Human Skin

Oxidative Medicine and Cellular Longevity
  • Special Issue
  • - Volume 2016
  • - Article ID 1920208
  • - Editorial

Plant-Derived Antioxidants in Disease Prevention

Renata Szymanska | Pavel Pospisil | Jerzy Kruk
  • Special Issue
  • - Volume 2016
  • - Article ID 9130976
  • - Review Article

Antioxidant Capacity Determination in Plants and Plant-Derived Products: A Review

Aurelia Magdalena Pisoschi | Aneta Pop | ... | Gabriel Predoi
  • Special Issue
  • - Volume 2016
  • - Article ID 4910829
  • - Clinical Study

Unbalanced Oxidant-Antioxidant Status: A Potential Therapeutic Target for Coronary Chronic Total Occlusion in Very Old Patients

Xia Li | Youdong Hu | ... | Qingna Zhao
  • Special Issue
  • - Volume 2016
  • - Article ID 1923754
  • - Research Article

Phytochemical Composition, Antioxidant Activity, and the Effect of the Aqueous Extract of Coffee (Coffea arabica L.) Bean Residual Press Cake on the Skin Wound Healing

Regina Celis Lopes Affonso | Ana Paula Lorenzen Voytena | ... | Marcelo Maraschin
  • Special Issue
  • - Volume 2016
  • - Article ID 4856761
  • - Research Article

Astragalus Polysaccharide Suppresses 6-Hydroxydopamine-Induced Neurotoxicity in Caenorhabditis elegans

Haifeng Li | Ruona Shi | ... | Zebo Huang
  • Special Issue
  • - Volume 2016
  • - Article ID 6949020
  • - Research Article

(−)-Epicatechin Prevents Blood Pressure Increase and Reduces Locomotor Hyperactivity in Young Spontaneously Hypertensive Rats

M. Kluknavsky | P. Balis | ... | I. Bernatova
  • Special Issue
  • - Volume 2016
  • - Article ID 8405957
  • - Research Article

The Chemical Profile of Senna velutina Leaves and Their Antioxidant and Cytotoxic Effects

Jaqueline Ferreira Campos | David Tsuyoshi Hiramatsu de Castro | ... | Edson Lucas dos Santos
  • Special Issue
  • - Volume 2016
  • - Article ID 4320374
  • - Review Article

Plant-Derived Agents for Counteracting Cisplatin-Induced Nephrotoxicity

Shreesh Ojha | Balaji Venkataraman | ... | Mohanraj Rajesh
  • Special Issue
  • - Volume 2016
  • - Article ID 2124638
  • - Review Article

Mechanisms and Clinical Application of Tetramethylpyrazine (an Interesting Natural Compound Isolated from Ligusticum Wallichii): Current Status and Perspective

Yingke Zhao | Yue Liu | Keji Chen
Oxidative Medicine and Cellular Longevity
 Journal metrics
Acceptance rate48%
Submission to final decision56 days
Acceptance to publication37 days
CiteScore7.300
Impact Factor5.076
 Submit