Oxidative Medicine and Cellular Longevity

New Insights into the Benefits of Polyphenols in Chronic Diseases


Status
Published

Lead Editor

1INRA, Montpellier, France

2University of Barcelona, Barcelona, Spain

3AZTI-Tecnalia, Biscay, Spain


New Insights into the Benefits of Polyphenols in Chronic Diseases

Description

Phenolic compounds, present in fruit and vegetables, wine, tea, extra virgin olive oil, chocolate, and other cocoa products, are important for the quality of plant based foods: they are responsible for the colour, substrates for enzymatic browning, and are also involved in flavour properties. Moreover, it has been demonstrated that polyphenols exert beneficial effects in chronic diseases, including cancer, cardiovascular diseases, and neurodegenerative disorders. Health effects of polyphenols are often attributed to their antioxidant activity which includes reduction or scavenging of ROS, chelation of transition metal ions, and inhibition of enzymes involved in oxidative stress. However, due to their poor bioavailability and extensive metabolism in the digestion process, their antioxidant effect in vivo is uncertain. The antioxidant action may, however, be exerted in the gastrointestinal tract. Some classes of polyphenols can reach colonic microbiota and after being metabolized can be absorbed and exhibit important biological activities. All these processes depend on the structure of the phenolic compounds but can also be modulated by reactions and interactions taking place in food or in the digestive tract.

This special issue intends to improve the knowledge on polyphenols for prevention and treatment of chronic diseases. We invite investigators to contribute original research articles, comprehensive reviews, and perspective articles aiming to evaluate the bioavailability and bioactivity of food polyphenols.

Potential topics include but are not limited to the following:

  • New methodologies for the analysis of food polyphenols
  • Bioavailability and bioactivity of food polyphenols
  • Human, animal, or in vitro studies: effects and dose of food polyphenols
  • Polyphenols for prevention and treatment of chronic diseases
  • Polyphenols in cardiovascular diseases
  • Polyphenols in obesity and metabolic disorders
  • Polyphenols in cancer
  • Polyphenols in neurodegenerative disorders
  • Design of novel functional foods and characterization of natural products and polyphenol extracts in relation to chronic diseases

Articles

  • Special Issue
  • - Volume 2017
  • - Article ID 1432071
  • - Editorial

New Insights into the Benefits of Polyphenols in Chronic Diseases

A. Tresserra-Rimbau | S. Arranz | A. Vallverdu-Queralt
  • Special Issue
  • - Volume 2017
  • - Article ID 2867630
  • - Research Article

An Alginate/Cyclodextrin Spray Drying Matrix to Improve Shelf Life and Antioxidant Efficiency of a Blood Orange By-Product Extract Rich in Polyphenols: MMPs Inhibition and Antiglycation Activity in Dysmetabolic Diseases

Maria Rosaria Lauro | Lucia Crascì | ... | Giovanni Puglisi
  • Special Issue
  • - Volume 2017
  • - Article ID 8315803
  • - Research Article

Effects of White Wine Consumption on Weight in Rats: Do Polyphenols Matter?

Ana Marija Milat | Ivana Mudnić | ... | Mladen Boban
  • Special Issue
  • - Volume 2017
  • - Article ID 7467962
  • - Review Article

Dietary Polyphenols in the Prevention of Stroke

A. Tressera-Rimbau | S. Arranz | ... | A. Vallverdú-Queralt
  • Special Issue
  • - Volume 2017
  • - Article ID 2962316
  • - Research Article

Neuroprotective and Cognitive-Enhancing Effects of Microencapsulation of Mulberry Fruit Extract in Animal Model of Menopausal Women with Metabolic Syndrome

Supannika Kawvised | Jintanaporn Wattanathorn | Wipawee Thukham-mee
  • Special Issue
  • - Volume 2017
  • - Article ID 6819281
  • - Research Article

Cardioprotective Effect of Resveratrol in a Postinfarction Heart Failure Model

Adam Riba | Laszlo Deres | ... | Robert Halmosi
  • Special Issue
  • - Volume 2017
  • - Article ID 4749131
  • - Review Article

Beer Polyphenols and Menopause: Effects and Mechanisms—A Review of Current Knowledge

Berner Andrée Sandoval-Ramírez | Rosa M. Lamuela-Raventós | ... | Anna Tresserra-Rimbau
  • Special Issue
  • - Volume 2017
  • - Article ID 5812401
  • - Review Article

Effects of Polyphenol Intake on Metabolic Syndrome: Current Evidences from Human Trials

Gemma Chiva-Blanch | Lina Badimon
  • Special Issue
  • - Volume 2017
  • - Article ID 6723931
  • - Review Article

Dietary Polyphenols, Mediterranean Diet, Prediabetes, and Type 2 Diabetes: A Narrative Review of the Evidence

Marta Guasch-Ferré | Jordi Merino | ... | Jordi Salas-Salvadó
  • Special Issue
  • - Volume 2017
  • - Article ID 5982809
  • - Research Article

Dietary Polyphenol Intake, but Not the Dietary Total Antioxidant Capacity, Is Inversely Related to Cardiovascular Disease in Postmenopausal Polish Women: Results of WOBASZ and WOBASZ II Studies

Anna M. Witkowska | Anna Waśkiewicz | ... | Wojciech Drygas
Oxidative Medicine and Cellular Longevity
 Journal metrics
Acceptance rate49%
Submission to final decision75 days
Acceptance to publication38 days
CiteScore4.520
Impact Factor4.868
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