Oxidative Medicine and Cellular Longevity

New Insights into the Benefits of Physical Activity and Exercise for Aging and Chronic Disease


Status
Published

1University of São Paulo, São Paulo, Brazil

2University of Bath, Bath, UK

3University of Iowa, Iowa City, USA


New Insights into the Benefits of Physical Activity and Exercise for Aging and Chronic Disease

Description

Chronic diseases such as cancer, cardiovascular and neurodegenerative diseases, diabetes, obesity, and skeletal muscle diseases are the leading cause of death and disability globally. Considering worldwide demographic shifts towards older age, the incidence of these conditions is increasing. Strategies to prevent and treat diseases associated with aging and lifestyle have become a priority for health science researchers, guideline groups, and policymakers. The most effective intervention to prevent and, in many cases, treat chronic disease, is the adoption of an active lifestyle; however, the cellular and molecular mechanisms by which physical activity and exercise bring about their effects remain poorly understood. This knowledge gap hinders the development of alternative strategies and therapies that could benefit individuals who cannot adhere to structured exercise regimens or make substantial changes to other aspects of their lifestyle.

In this special issue, we invite investigators to contribute narrative reviews as well as original research articles. Basic, translational, or clinical contributions are welcome. Articles should improve our understanding of how physical activity and exercise promote healthy aging, counter the development of disease, and facilitate the treatment of chronic conditions. Subjects of the papers could contain the cellular and molecular mechanisms by which physical activity and/or exercise regulate and other topics.

Potential topics include but are not limited to the following:

  • Immunological, inflammatory, and redox processes
  • Energy balance and metabolic homeostasis
  • Tissue-specific processes including tissue cross-talk
  • Obesity, sarcopenia, and cachexia
  • Risk, etiology, or treatment of diabetes, cancer, and cardiovascular and neurodegenerative diseases

Articles

  • Special Issue
  • - Volume 2017
  • - Article ID 2503767
  • - Editorial

New Insights into the Benefits of Physical Activity and Exercise for Aging and Chronic Disease

James E. Turner | Vitor A. Lira | Patricia C. Brum
  • Special Issue
  • - Volume 2017
  • - Article ID 2578950
  • - Research Article

Effect of Multicomponent Training on Blood Pressure, Nitric Oxide, Redox Status, and Physical Fitness in Older Adult Women: Influence of Endothelial Nitric Oxide Synthase (NOS3) Haplotypes

Atila Alexandre Trapé | Elisangela Aparecida da Silva Lizzi | ... | Carlos Roberto Bueno Júnior
  • Special Issue
  • - Volume 2017
  • - Article ID 1549014
  • - Research Article

Exercise Training Restores Cardiac MicroRNA-1 and MicroRNA-29c to Nonpathological Levels in Obese Rats

André C. Silveira | Tiago Fernandes | ... | Edilamar M. Oliveira
  • Special Issue
  • - Volume 2017
  • - Article ID 4234765
  • - Review Article

Does Regular Exercise Counter T Cell Immunosenescence Reducing the Risk of Developing Cancer and Promoting Successful Treatment of Malignancies?

James E. Turner | Patricia C. Brum
  • Special Issue
  • - Volume 2017
  • - Article ID 4865756
  • - Review Article

Targeting Endothelial Function to Treat Heart Failure with Preserved Ejection Fraction: The Promise of Exercise Training

Andreas B. Gevaert | Katrien Lemmens | ... | Emeline M. Van Craenenbroeck
  • Special Issue
  • - Volume 2017
  • - Article ID 7921363
  • - Research Article

High-Intensity Exercise Reduces Cardiac Fibrosis and Hypertrophy but Does Not Restore the Nitroso-Redox Imbalance in Diabetic Cardiomyopathy

Ulises Novoa | Diego Arauna | ... | Daniel R. Gonzalez
  • Special Issue
  • - Volume 2017
  • - Article ID 8148742
  • - Research Article

Neutrophil and Monocyte Bactericidal Responses to 10 Weeks of Low-Volume High-Intensity Interval or Moderate-Intensity Continuous Training in Sedentary Adults

David B. Bartlett | Sam O. Shepherd | ... | Janet M. Lord
  • Special Issue
  • - Volume 2017
  • - Article ID 5608287
  • - Research Article

Association of the Composite Inflammatory Biomarker GlycA, with Exercise-Induced Changes in Body Habitus in Men and Women with Prediabetes

David B. Bartlett | Cris A. Slentz | ... | William E. Kraus
Oxidative Medicine and Cellular Longevity
 Journal metrics
Acceptance rate48%
Submission to final decision56 days
Acceptance to publication37 days
CiteScore7.300
Impact Factor5.076
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