Oxidative Medicine and Cellular Longevity

Oxidative Stress in Cardio-Oncology


Publishing date
01 Aug 2022
Status
Closed
Submission deadline
18 Mar 2022

Lead Editor

1Jiangxi Provincial People’s Hospital Affiliated to Nanchang University, Nanchang, China

2Royal North Shore Hospital, Sydney, Australia

This issue is now closed for submissions.
More articles will be published in the near future.

Oxidative Stress in Cardio-Oncology

This issue is now closed for submissions.
More articles will be published in the near future.

Description

Improvements in screening strategies and novel anti-tumor drugs promote longer survival of cancer patients, but many drugs also have serious side effects including both short-term and long-term cardiotoxicity. Oxidative stress (OS) is the major effect of anti-tumor drug-induced cardiotoxicity and is caused by an imbalance between reactive oxygen species (ROS) and endogenous antioxidants in response to injury, leading to myocardial toxicity.

Though the role of oxidative stress in anti-tumor drug-induced cardiotoxicity has been identified, prevention strategies have been far from successful. Many studies describe anti-tumor drug therapy for cardiotoxicity, including dexrazoxane, natural plant extracts, animal extracts, or chemically synthesized artificial antioxidants. The success of animal modeling in various drug efficacy studies does not translate to good results in humans, and, even if it did, large-scale clinical trials are lacking.

This Special Issue aims to summarize the present knowledge of oxidative stress in anti-tumor drug-induced cardiotoxicity including cell molecular mechanisms, prevention and treatment strategies, drug research, and population experiments. Original research and review articles are welcome.

Potential topics include but are not limited to the following:

  • The prevention of oxidative stress induced by anti-tumor drugs
  • Subcellular organelle damage in anti-tumor drug-induced oxidative stress
  • Dysregulation of protein regulation in anti-tumor drug-induced oxidative stress
  • Role of nitric oxide synthase in anti-tumor drug-induced cardiotoxicity
  • Role of NADPH oxidase in anti-tumor drug-induced cardiotoxicity

Articles

  • Special Issue
  • - Volume 2022
  • - Article ID 3771610
  • - Research Article

Comparative Analysis of Early Clinical Features and Complications of Different Types of Acute Pancreatitis

Hongsheng Wu | Keqiang Ma | ... | Tiansheng Cao
  • Special Issue
  • - Volume 2022
  • - Article ID 9386095
  • - Review Article

Potential Benefits of Music Therapy on Stroke Rehabilitation

Chengyan Xu | Zixia He | ... | Fei Huang
  • Special Issue
  • - Volume 2022
  • - Article ID 7427255
  • - Research Article

A Novel Approach Combined with MIPO Technique for the Treatment of Type C Pilon Fractures

Youhao Chen | Haoming Wang | ... | Xiaohua Chen
  • Special Issue
  • - Volume 2022
  • - Article ID 2129303
  • - Research Article

An Enhanced Priori Knowledge GAN for CT Images Generation of Early Lung Nodules with Small-Size Labelled Samples

Xun Wang | Zhiyong Yu | ... | Pan Zheng
  • Special Issue
  • - Volume 2022
  • - Article ID 6189170
  • - Review Article

Glymphatic System: Emerging Therapeutic Target for Neurological Diseases

Xianjun Xuan | Guoyi Zhou | ... | Jiaqi Zhou
  • Special Issue
  • - Volume 2022
  • - Article ID 3185320
  • - Research Article

Clinical Efficacy of PEG-IFNα-2a and PEG-IFNα-2b in the Treatment of Hepatitis B e Antigen-Positive Hepatitis B and Their Value in Improving Inflammatory Factors and Hemodynamics in Patients: A Comparative Study

Nina Jia | Wei Gao | ... | Jie Yang
  • Special Issue
  • - Volume 2022
  • - Article ID 9266178
  • - Research Article

Protective Effects of Amauroderma rugosum on Doxorubicin-Induced Cardiotoxicity through Suppressing Oxidative Stress, Mitochondrial Dysfunction, Apoptosis, and Activating Akt/mTOR and Nrf2/HO-1 Signaling Pathways

Jingjing Li | Yanfen Cheng | ... | George Pak-Heng Leung
  • Special Issue
  • - Volume 2022
  • - Article ID 2218140
  • - Research Article

Characterization of the Prognostic Values of CXCL Family in Epstein–Barr Virus Associated Gastric Cancer

Li Mu | Shun Hu | ... | Sheng Zhang
  • Special Issue
  • - Volume 2022
  • - Article ID 6503504
  • - Research Article

Mild Hypothermia Promotes Ischemic Tolerance and Survival of Neural Stem Cell Grafts by Enhancing Global SUMOylation

Heng Cai | Xiaofang Ma | ... | Zhiqing Li
  • Special Issue
  • - Volume 2022
  • - Article ID 3050007
  • - Research Article

Modified Trabeculectomy versus Glaucoma Drainage Implant Surgery: A Retrospective Comparative Study for Refractory Glaucoma Treatment

Yuan He | Beilei He | ... | Xiaoli Pu
Oxidative Medicine and Cellular Longevity
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Acceptance rate33%
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