Neurodegenerative diseases are a diverse group of disorders that are characterized by the progressive degeneration of the structure and function of the central or peripheral nervous system. Neurodegenerative disorders are conditions that result in degeneration or death of nerve cells. This causes problems with mental function (i.e. dementias) or movement.

These diseases affect millions of people worldwide, can be severe or life-threatening, and most are incurable. Treatments may help to improve symptoms, increase mobility, and relieve pain. These disorders include Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, motor neuron disease, and prion disease. In recent years, we have witnessed a considerable number of studies investigating the role of oxidative stress in these diseases.

The goal of this Special Issue is to give an overview of the role of oxidative stress in neurodegenerative diseases through the publication of both original research, review articles and systematic reviews.

Potential topics include but are not limited to the following:

• Oxidative stress and cellular / molecular neurodegeneration
• Oxidative stress and neurobiology of disease
• Oxidative stress and neuropharmacology in neurodegenerative disease
• Oxidative stress and neuroplasticity in neurodegeneration