Research Article

Multisensory Stimulation and Priming (MuSSAP) in 4-10 Months Old Infants with a Unilateral Brain Lesion: A Pilot Randomised Clinical Trial

Table 1

Participant demographic and baseline (T0) characteristics.

EI-UL ()EI-UL-MuSSAP ()Typical ()

(Corrected) age in months, mean (range)5.8 (4.3-8.8)6.5 (3.8-8.3)6.6 (4.0-8.8)
Gender, M/F, 3/57/15/3
Preterm (GA<37 wk)/term, n2/63/50/8
Affected hemisphere left/right, 3/54/4n.a.
Neuroimaging
 PAIS/PVHI/nonspecific, 5/2/13/5/0n.a.
HAI, BSID-III-NL, and GMFM scores: mean (SD)
 HAI Both Hands Measure44.0 (8.0)a49.3 (11.3)a82.5 (17.5)
 HAI Affected Hand Sum Score5.5 (3.9)a7.4 (7.1)a22.3 (2.3)
 BSID-III-NL GM raw score16.9 (4.6)a17.6 (3.9)a23.5 (4.7)
 BSID-III-NL FM raw score13.5 (3.5)a16.4 (2.9)119.4 (4.9)
 GMFM total score12.3 (6.0)a12.8 (3.5)a20.6 (6.6)
ITQOL-SF47 scores: mean (range)
 Physical abilities69 (53-92)63 (20-93)99 (93-100)1
 Growth and development85 (55-100)76 (55-100)93 (75-100)
 Bodily pain/discomfort88 (75-100)70 (38-100)83 (63-100)
 Temperament and moods82 (71-96)72 (42-88)81 (63-96)
 General health perceptions66 (31-83)61 (27-89)88 (79-93)
 Parental impact-emotional84 (69-100)74 (44-100)95 (88-100)
 Parental impact-time88 (67-100)83 (42-100)96 (83-100)
 Family cohesion91 (60-100)84 (60-100)91 (85-100)

Corrected age was calculated for infants born <37 weeks. Abbreviations: EI-UL: Early Intensive-Upper Limb intervention; MuSSAP: Multi Sensory Stimulation And Priming; MRI: Magnetic Resonance Imaging; PAIS: perinatal arterial ischemic stroke; PVHI: periventricular haemorrhagic infarction; HAI: Hand Assessment for Infants; BSID-III-NL: Bayley Scales of Infant and Toddler Development-Third Edition-Dutch version; GMFM: Gross Motor Function Measure-88; ITQOL; Infant and Toddler Quality Of Life questionnaire Short Form 47. 1, asignificantly different compared to typically developing children ().