Multisensory Stimulation and Priming (MuSSAP) in 4-10 Months Old Infants with a Unilateral Brain Lesion: A Pilot Randomised Clinical Trial
Table 1
Participant demographic and baseline (T0) characteristics.
EI-UL ()
EI-UL-MuSSAP ()
Typical ()
(Corrected) age in months, mean (range)
5.8 (4.3-8.8)
6.5 (3.8-8.3)
6.6 (4.0-8.8)
Gender, M/F,
3/5
7/1
5/3
Preterm (GA<37 wk)/term, n
2/6
3/5
0/8
Affected hemisphere left/right,
3/5
4/4
n.a.
Neuroimaging
PAIS/PVHI/nonspecific,
5/2/1
3/5/0
n.a.
HAI, BSID-III-NL, and GMFM scores: mean (SD)
HAI Both Hands Measure
44.0 (8.0)a
49.3 (11.3)a
82.5 (17.5)
HAI Affected Hand Sum Score
5.5 (3.9)a
7.4 (7.1)a
22.3 (2.3)
BSID-III-NL GM raw score
16.9 (4.6)a
17.6 (3.9)a
23.5 (4.7)
BSID-III-NL FM raw score
13.5 (3.5)a
16.4 (2.9)1
19.4 (4.9)
GMFM total score
12.3 (6.0)a
12.8 (3.5)a
20.6 (6.6)
ITQOL-SF47 scores: mean (range)
Physical abilities
69 (53-92)
63 (20-93)
99 (93-100)1
Growth and development
85 (55-100)
76 (55-100)
93 (75-100)
Bodily pain/discomfort
88 (75-100)
70 (38-100)
83 (63-100)
Temperament and moods
82 (71-96)
72 (42-88)
81 (63-96)
General health perceptions
66 (31-83)
61 (27-89)
88 (79-93)
Parental impact-emotional
84 (69-100)
74 (44-100)
95 (88-100)
Parental impact-time
88 (67-100)
83 (42-100)
96 (83-100)
Family cohesion
91 (60-100)
84 (60-100)
91 (85-100)
Corrected age was calculated for infants born <37 weeks. Abbreviations: EI-UL: Early Intensive-Upper Limb intervention; MuSSAP: Multi Sensory Stimulation And Priming; MRI: Magnetic Resonance Imaging; PAIS: perinatal arterial ischemic stroke; PVHI: periventricular haemorrhagic infarction; HAI: Hand Assessment for Infants; BSID-III-NL: Bayley Scales of Infant and Toddler Development-Third Edition-Dutch version; GMFM: Gross Motor Function Measure-88; ITQOL; Infant and Toddler Quality Of Life questionnaire Short Form 47. 1,asignificantly different compared to typically developing children ().