Racial/Ethnic Patterns in Prostate Cancer Outcomes in an Active Surveillance Cohort

Table 3

Multivariable Cox proportional hazards regression predicting overall survival in a cohort of subjects with prostate cancer (CaP) followed on active surveillance (AS) for primary treatment (𝑁=886).

Characteristic	HOR^1 (95% CI^2)	P value
Age at diagnosis, years		0.1122
<60	Referent	—
60–60.9	1.837 (1.016–3.322)	0.0441
≥70	1.856 (1.026–3.357)	0.0408
Race
White	Referent	—
Black	1.106 (0.805–1.519)	0.5362
Comorbidities		0.2714
0	Referent	—
1	1.235 (0.877–1.738)	0.2271
2	1.029 (0.700–1.512)	0.8847
3 or more	1.373 (0.952–1.978)	0.0895
D’Amico et al. risk strata		<0.0001
Low	Referent	—
Intermediate	1.612 (1.162–2.237)	0.0042
High	2.627 (1.927–3.580)	<0.0001
Secondary treatment type		<0.0001
None (AS only)	Referent	—
RP^3	0.022 (0.011–0.043)	<0.0001
EBRT-Br^4	0.052 (0.031–0.087)	<0.0001
HT^5	0.107 (0.069–0.167)	<0.0001
Dx^6 to secondary treatment, months	0.970 (0.965–0.976)	<0.0001

¹HOR: hazard Odds Ratio.
²CI: confidence Interval.
³RP: radical prostatectomy.
⁴ EBRT-BR: external beam radiation therapy and Brachytherapy, combined.
⁵HT: hormone therapy.
⁶ Dx: diagnosis of CaP.