Metastasis Update: Human Prostate Carcinoma Invasion via Tubulogenesis
Figure 4
Budding lesions are devoid of basal cells and lack laminin 5 deposition and become exposed to laminin 10. Serial sections containing cell clusters (white arrows) were stained either for laminin 332 (LAM5) or laminin 511 (LAM10) and the basal cell-specific marker, cytokeratin 5 and 14 (CK5-14).
