Metabolic Complications and Increased Cardiovascular Risks as a Result of Androgen Deprivation Therapy in Men with Prostate Cancer

Table 4

Effect of ADT on body composition.

	Duration	Lean body mass	Abdominal area	BMI/Weight	Fat mass
Basaria et al. [27]		NS	NR	Higher in ADT group*	Higher at total body, trunk and extremities
Smith et al. [25]	3 months	Decreased 1.7 kg, 𝑃=0.016	NR	NR	Increased 1.7 Kg
Smith et al. [29]	4 months	Decreased 2.7%*	Increased by 3.9+1.2%, 𝑃=0.003	Increased by 2.4+0.8%	Increased by 9.4+1.7%*
Chen et al. [30]	1–5 yr	NS	NR	Higher in ADT group*	Higher in ADT
Lee et al. [31]	12 Months	Decreased by 2%*	NR	NR	Increased by 6.6%*

NS: Not significant; NR: Not reported  *𝑃<0.001.