Research Article
Growth and Progression of TRAMP Prostate Tumors in Relationship to Diet and Obesity
Table 1
End-point comparisons for TRAMP GTG male mice§.
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Final body weight (g) |
Age at tumor palpation (weeks) |
Age at death (weeks) |
GUT weight (g) | Tumor differentiation |
Percent with metastasis | | | Well | Moderate | Poor |
| | GTG-6 | | | | | | | | | | Obese () | 51.78 ± 5.30a | 27.67 ± 4.91 () | 35.75 ± 4.59 | 6.23 ± 1.40 | 50% | 25% | 25% | 25% | | Lean () | 36.07 ± 3.75b | 22.0 ± 3.51 () | 28.33 ± 8.84 | 6.30 ± 1.96 | 33% | 0 | 67% | 67% | | PBS () | 36.92 ± 1.33b | 29.36 ± 1.61 () | 38.33 ± 1.92 | 7.84 ± 0.84 | 60% | 7% | 33% | 47% | | GTG-26 | | | | | | | | | | Obese () | 48.61 ± 2.60a | 33.38 ± 0.94 | 42.13 ± 1.22 | 9.10 ± 1.54 () | 50% | 50% | 0 | 13% | | *Lean () | 39.08 ± 2.46b | 33.50 ± 1.09 | 43.00 ± 1.67 | 8.90 ± 1.45 () | 60% | 20% | 0 | 20% | | PBS () | 36.65 ± 1.63b | 32.30 ± 1.10 | 41.30 ± 1.40 | 8.16 ± 1.0 () | 58% | 8% | 33% | 33% |
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§columns with different letters indicate a significant difference among the groups.
*pathology report not received for one mouse in this group.
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