Research Article
Growth and Progression of TRAMP Prostate Tumors in Relationship to Diet and Obesity
Table 3
Overview of NE status of TRAMP DIO study tumors.
| Group | Percent NE positive | NE status | Initial body weight | Body weight increase (6–18 weeks) | Final body weight | Age at tumor detection | Age at death | GUT weight | High grade (%) |
| Obesity prone | 37% (7/19) | Positive | 20.8 ± 0.9 | 14.1 ± 0.6 | 39.1 ± 2.7 | | | | (100)x 7/7 | Negative | 20.8 ± 0.7 | 13.1 ± 0.4 | 43.9 ± 2.1 | 31.4 ± 0.9 | 46.3 ± 0.9 | 11.4 ± 0.9 | (18) 2/11 | Overweight | 21% (3/14) | Positive | 22.8 ± 1.1 | 9.5 ± 0.4 | | | | 9.5 ± 0.8 | (100) 2/2 | Negative | 21.7 ± 0.5 | 9.5 ± 0.2 | 41.2 ± 1.2 | 33.7 ± 1.6 | 44.6 ± 1.5 | 9.9 ± 1.0 | (56) 5/9 | Obesity resistant | 46% (6/13) | Positive | 21.1 ± 0.5 | 7.2 ± 0.7 | 35.0 ± 2.7 | 26.7 ± 2.6 | 35.0 ± 4.6 | 7.7 ± 1.6 | (100) 6/6 | Negative | 22.3 ± 0.5 | 8.0 ± 0.2 | 40.6 ± 3.5 | 29.3 ± 1.6 | 42.1 ± 2.9 | 9.4 ± 10.5 | (57) 4/7 | All high-fat diet mice | 35% (16/46) | Positive | 21.3 ± 0.5 | 10.2 ± 0.8 | | | | | (100)x 15/15 | Negative | 21.5 ± 0.3 | 11.0 ± 0.4 | 42.1 ± 1.2 | 31.8 ± 0.8 | 44.7 ± 0.9 | 10.4 ± 0.6 | (41) 11/27 | Low fat | 35% (6/17) | Positive | 19.7 ± 1.3 | 8.1 ± 1.8 | 36.6 ± 2.7 | | | | (100)x 6/6 | Negative | 21.2 ± 0.6 | 8.0 ± 0.7 | 39.7 ± 1.7 | 31.7 ± 1.2 | 45.8 ± 1.6 | 10.4 ± 1.0 | (20) 2/10 |
|
|
A significant difference () within each group is designated as x.
|