Analysis of Preoperative Detection for Apex Prostate Cancer by Transrectal Biopsy
Table 4
Univariate and multivariate analysis of factors for detecting apex cancer among clinicopathological factors.
True positive
False negative
Univariate analysis
Multivariate analysis
value
95% CI
Age, mean years
65.2
65.3
0.898
BMI, mean kg/m2
22.4
22.6
0.677
PSA, mean ng/mL
9.69
8.10
0.113
F/T ratio, mean %
12.8
16.4
0.024*
0.953–1.100
0.737
Prostate volume, mean mL
32.1
32.5
0.890
Clinical T stage
T1c
50
40
T2a–c
12
12
0.954
⩾T3a
3
1
Biopsy Gleason score
6
20
24
7 8
41
27
0.197
9 10
4
2
Positive core number, mean
3.66
2.43
0.0002*
0.574–1.133
0.215
pathological T stage
T2a–c
33
39
0.010
0.234–2.632
0.696
⩾T3a
32
14
RP apex Gleason score
6
13
13
7 8
46
35
0.431
9 10
6
5
Apex tumor volume, mean mL
0.802
0.193
<0.0001*
0.004–0.192
0.0002*
Total tumor volume, mean mL
2.76
1.76
0.016*
0.572–1.001
0.051
True positive: RP specimen positive and biopsy positive, false negative: RP specimen positive and biopsy negative, BMI: body mass index, PSA: prostate specific antigen, F/T: free total PSA ratio, RP: radical prostatectomy, *statistically significant.
