CHEK2^∗1100delC Mutation and Risk of Prostate Cancer

Table 1

Characteristics and results of 5 prostate cancer studies.

Carrier/Total	Population	Country	OR/HR (95% CI)	value	Ref.
21/3,750	Unselected cases	PL	3.2 (1.4–7.5)	0.009	[20]
4/412	Familial cases		5.5 (1.6–19.0)	0.01
7/3,956	Controls		Reference
1/145	Without family history	SW	0.70 (0.07–6.78)	0.76	[21]
4/254	Familial cases		1.61 (0.36–7.27)	0.53
3/305	Controls		Reference
7/537	Unselected cases	FI	3.14 (0.65–15.16)	0.15	[22]
4/120	Familial cases		8.24 (1.49–45.54)	0.02
2/480	Controls		Reference
4/178	Cases	US	NA	NA	[23]
1/400	Without family history		NA	NA
1/298	Familial cases		NA	NA
0/423	Controls		NA	NA
2/114	Cases	DE	2.3 (0.6–9.5)	NA	[24]
21/4,094	Controls		Reference
36/5,124	Unselected cases	Pooled	1.98 (1.23–3.18)	0.004	Combined
13/1,084	Familial cases		3.39 (1.78–6.47)	0.0001
33/9,258	Controls		Reference

PL: Poland, SW: Sweden, FI: Finland, US: United States, DE: Denmark, NA: not available.