Analysis of Prostate Cancer Susceptibility Variants in South African Men: Replicating Associations on Chromosomes 8q24 and 10q11

Table 1

Clinical characteristics among South African cases and controls.

Variables of interest	Mixed Ancestry		White		value
	Controls ( = 178)	Cases ( = 331)	Controls ( = 145)	Cases ( = 155)
Median age (years)^a	60	67	64	70	<0.001
Median PSA (ng/mL)^b	0.89	18.4	0.86	11.7	<0.001
Gleason ≥ 7^‡		84/177 (41.7%)		42/96 (43.8%)	0.557
Stage ≥ 2b^‡		118/283 (41.7%)		39/123 (31.7%)	0.058
Metastasis^‡		30/252 (11.9%)		4/116 (3.4%)	0.009

For each of the respective population groups, when comparing the median age between cases and controls.
^bFor each of the respective population groups, when comparing the median PSA between cases and controls.
^‡Gleason score, tumour stage, and/or metastases information were missing from the medical records of some of the clinically confirmed prostate cancer cases. Therefore, the numbers and percentages shown are for the available information and not that of the total number of cases included in the study for each population group.