Thioredoxin 1 in Prostate Tissue Is Associated with Gleason Score, Erythrocyte Antioxidant Enzyme Activity, and Dietary Antioxidants

Table 3

Association between prostate tissue Trx 1 and erythrocyte glutathione peroxidase activity.

	Erythrocyte glutathione peroxidase (GPx)
	T1		T2		T3		Total
		%		%		%
Malignant Trx 1
0	2	(50)	0	(0)	2	(50)	4
1	1	(14)	5	(71)	1	(14)	7
2	7	(35)	3	(15)	10	(50)	20
3	6	(42)	7	(50)	1	(7)	14
Fisher’s exact test,
Benign Trx 1
0	0	(0)	1	(100)	0	(0)	1
1	11	(39)	9	(32)	8	(28)	28
2	3	(23)	4	(30)	6	(46)	13
3	2	(66)	1	(33)	0	(0)	3
Fisher’s exact test,
ΔTrx 1
−2	1	(50)	0	(0)	1	(50)	2
−1	1	(25)	2	(50)	1	(25)	4
0	4	(28)	4	(28)	6	(42)	14
1	7	(41)	5	(29)	5	(29)	17
2	3	(42)	3	(42)	1	(14)	7
3	0	(0)	1	(100)	0	(0)	1
Total	16		15		14		45
Fisher’s exact test,

ΔTrx 1: difference in Trx 1 level between malignant and benign prostate cells.
Median values of tertiles of GPx activity are as follows: T1: 356.6 mol/min/mL; T2: 815.0 nmol/min/mL; T3: 1258.2 nmol/min/mL.