Thioredoxin 1 in Prostate Tissue Is Associated with Gleason Score, Erythrocyte Antioxidant Enzyme Activity, and Dietary Antioxidants
Table 6
Association between prostate tissue Trx 1 and erythrocyte superoxide dismutase activity.
Erythrocyte superoxide dismutase (SOD)
T1
T2
T3
Total
%
%
%
Malignant Trx 1
0
2
(50)
1
(25)
1
(25)
4
1
1
(14)
3
(42)
3
(42)
7
2
5
(25)
7
(35)
8
(40)
20
3
7
(50)
5
(35)
2
(14)
14
Fisher’s exact test,
Benign Trx 1
0
0
(0)
1
(100)
0
(0)
1
1
11
(39)
8
(28)
9
(32)
28
2
2
(15)
6
(46)
5
(38)
13
3
2
(66)
1
(33)
0
(0)
3
Fisher’s exact test,
ΔTrx 1
−2
1
(50)
0
(0)
1
(50)
2
−1
1
(25)
2
(50)
1
(25)
4
0
3
(21)
6
(42)
5
(35)
14
1
6
(35)
6
(35)
5
(29)
17
2
4
(57)
1
(14)
2
(28)
7
3
0
(0)
1
(100)
0
(0)
1
Total
16
15
14
45
Fisher’s exact test,
ΔTrx 1: difference in Trx 1 level between malignant and benign prostate cells. Median values of tertiles of SOD activity are as follows: T1: 66.3 units/mL; T2: 75.9 units/mL; T3: 80.8 units/mL.