Thioredoxin 1 in Prostate Tissue Is Associated with Gleason Score, Erythrocyte Antioxidant Enzyme Activity, and Dietary Antioxidants

Table 8

Summary of associations between prostate cancer Gleason score, antioxidant enzymes, and dietary total antioxidant capacity and Trx 1 levels in prostate tissue based on results of the present study: (+) indicates a positive association and (−) a negative association; empty cells indicate no evidence of an association.

	Trx 1
	Malignant tissue	Benign tissue
Gleason score	+	+
GPx	−
GR
GST
SOD
TAC		−

GPx: erythrocyte glutathione peroxidase activity; GR: erythrocyte glutathione reductase activity; GST: erythrocyte glutathione S-transferase activity; SOD: erythrocyte superoxide dismutase activity; TAC: dietary total antioxidant capacity.
While the association between Gleason score and Trx 1 in malignant tissue was not statistically significant (), the data in Table 2 displays evidence of a positive association.