Clinical Study

Triptorelin in the Relief of Lower Urinary Tract Symptoms in Advanced Prostate Cancer Patients: The RESULT Study

Table 4

Change in intensity of symptoms from baseline to each visit for patients from the effectiveness population who underwent radiotherapy or a TURP.

At baseline ( = 53)
Mild symptomsModerate symptomsSevere symptoms

At week 24 ( = 46)
( = 0.017* versus baseline)
 No symptoms1 (2.2%)0 (0%)0 (0%)
 Mild symptoms14 (30.4%)9 (19.6%)1 (2.2%)
 Moderate symptoms1 (2.2%)16 (34.8%)0 (0%)
 Severe symptoms1 (2.2%)1 (2.2%)2 (4.3%)
At week 48 ( = 49)
( = 0.027* versus baseline)
 No symptoms2 (4.1%)0 (0%)0 (0%)
 Mild symptoms15 (30.6%)12 (24.5%)0 (0%)
 Moderate symptoms3 (6.1%)13 (26.5%)2 (4.1%)
 Severe symptoms0 (0%)1 (2.0%)1 (2.0%)
At last available visit ( = 53)
( = 0.005* versus baseline)
 No symptoms2 (3.8%)0 (0%)0 (0%)
 Mild symptoms15 (28.3%)14 (26.4%)1 (1.9%)
 Moderate symptoms3 (5.7%)14 (26.4%)2 (3.8%)
 Severe symptoms0 (0%)1 (1.9%)1 (1.9%)

Bhapkar’s test for homogeneity. Note: percentages are based on the number of patients with available responses. To operate Bhapkar’s test, a frequency equal to 0 was replaced by 0.001.