Research Article

Influence of In Utero Maternal and Neonate Factors on Cord Blood Leukocyte Telomere Length: Clues to the Racial Disparity in Prostate Cancer?

Table 2

Geometric mean relative telomere length in umbilical cord blood leukocytes by maternal and neonate factors, overall and by race, males in the hormones in umbilical cord blood study.

Geometric mean (95% CI)
UnadjustedAdjusted for raceBlackWhite

Maternal factors
Age (years)
 ≤192.60 (2.21–3.05)2.58 (2.19–3.05)2.70 (2.26–3.23)2.35 (1.67–3.30)
 20–252.72 (2.29–3.22)2.70 (2.26–3.22)2.73 (2.27–3.29)2.67 (1.83–3.90)
 26–313.01 (2.59–3.49)3.03 (2.59–3.53)3.23 (2.48–4.20)2.93 (2.41–3.56)
 ≥322.58 (2.23–3.00)2.59 (2.23–3.02)2.37 (1.86–3.03)2.70 (2.20–3.30)
Relative change per year 1.001.001.001.01
-trend0.91.00.60.6

Parity
 02.65 (2.38–2.96)2.65 (2.37–2.96)2.61 (2.20–3.11)2.68 (2.30–3.11)
 12.96 (2.52–3.48)2.96 (2.52–3.48)2.77 (2.24–3.42)3.22 (2.48–4.18)
 22.82 (2.27–3.50)2.82 (2.27–3.51)2.99 (2.28–3.93)2.58 (1.78–3.73)
 ≥32.52 (2.00–3.16)2.52 (2.00–3.19)2.67 (2.07–3.44)2.05 (1.21–3.46)
Relative change per birth0.990.991.000.98
-trend0.80.81.00.7

Neonate factors
Birth weight (g)
 ≤30252.68 (2.30–3.14)2.67 (2.28–3.13)2.76 (2.29–3.32)2.56 (1.96–3.35)
 3026–33732.52 (2.16–2.95)2.51 (2.14–2.95)2.58 (2.16–3.09)2.40 (1.80–3.21)
 3374–36343.01 (2.58–3.52)3.02 (2.58–3.54)2.49 (1.95–3.18)3.36 (2.74–4.13)
 ≥36352.71 (2.32–3.17)2.73 (2.32–3.20)3.29 (2.53–4.29)2.48 (2.04–3.02)
Relative change per SD (399.99)1.001.001.001.00
-trend0.91.01.00.9

Placental weight (g)
 ≤5852.48 (2.12–2.90)2.48 (2.12–2.90)2.52 (2.06–3.09)2.42 (1.85–3.16)
 586–6592.90 (2.48–3.40)2.90 (2.48–3.40)2.76 (2.23–3.41)3.07 (2.39–3.95)
 660–7602.77 (2.37–3.24)2.77 (2.37–3.25)2.84 (2.33–3.48)2.67 (2.05–3.49)
 ≥7612.77 (2.37–3.24)2.77 (2.36–3.25)2.81 (2.14–3.69)2.75 (2.23–3.39)
Relative change per SD (138.01)1.021.021.061.00
-trend0.60.60.41.0