Influence of In Utero Maternal and Neonate Factors on Cord Blood Leukocyte Telomere Length: Clues to the Racial Disparity in Prostate Cancer?

Table 3

Relative change in the geometric mean umbilical cord blood leukocyte telomere length per standard deviation change in umbilical cord blood hormone concentrations, overall and by race, males in the hormones in umbilical cord blood study.

Hormone	Standard deviation	Unadjusted		Adjusted for race		Black		White
		Relative change	-trend	Relative change	-trend	Relative change	-trend	Relative change	-trend
Testosterone (ng/mL)	0.47	0.99	0.7	0.99	0.7	0.99	0.7	0.99	0.9
Estradiol (pg/mL)	5,464	0.97	0.4	0.97	0.4	0.98	0.8	0.96	0.5
SHBG (nmol/L)	5.00	0.97	0.4	0.97	0.4	0.93	0.1	1.01	0.9
Androstanediol glucuronide (ng/mL)	15.11	1.11	0.01	1.11	0.01	1.12	0.01	1.08	0.3
IGF-1 (ng/mL)	51.76	1.02	0.6	1.02	0.6	1.05	0.6	1.02	0.8
IGF-2 (ng/mL)	93.43	1.03	0.4	1.04	0.4	1.09	0.1	1.00	0.9
IGFBP-3 (ng/mL)	394.8	0.99	0.7	0.98	0.7	0.99	0.9	0.98	0.7
Leptin (pg/mL)	8,897	1.00	0.9	1.00	0.9	1.15	0.3	0.99	0.8
Vitamin D (ng/mL)	9.45	0.97	0.4	0.96	0.3	1.01	0.9	0.93	0.2
Molar ratios of
Testosterone/SHBG	0.13	1.03	0.5	1.03	0.5	1.04	0.4	1.01	0.9
Estradiol/SHBG	1.09	1.00	0.9	0.99	0.9	1.05	0.5	0.97	0.6
IGF-1/IGFBP-3	0.08	1.06	0.1	1.07	0.1	1.05	0.4	1.08	0.2
IGF-2/IGFBP-3	0.19	1.06	0.1	1.06	0.1	1.09	0.08	1.02	0.7