Prostate Radiotherapy in the Era of Advanced Imaging and Precision Medicine

Table 3

Randomized controlled trials evaluating the efficacy and toxicity of extreme hypofractionated radiation regimens.

Trial	Inclusion criteria	Dose (dose per fraction)
HYPO-RT-PC [54]	Intermediate risk	78 Gy (2 Gy) versus; 42.7 Gy (6.1 Gy)
PACE [55]	Low-intermediate risk	() Radical prostatectomy versus 36.25 Gy (7.25 Gy); () 78 Gy (2 Gy) versus 36.25 Gy (7.25 Gy)
Proton cooperative group [56]	Low-intermediate risk	79.2 Gy (1.8 Gy) versus; 38 Gy (7.6 Gy)