Research Article

Predicting Low-Risk Prostate Cancer from Transperineal Saturation Biopsies

Figure 1

Decision curve analysis, demonstrating the net benefit, as measured by rate of nontreating men for low-risk prostate cancer, using the five decision-making strategies as listed in the legend. Threshold probability is the threshold probability of low-risk PC at which an individual considers the benefit of treatment for PC equivalent to the harm of overtreatment for low-risk disease, and thus it reflects how the individual weights the benefits and harms associated with this decision. The highest curve at any given threshold probability is the optimal decision-making strategy to maximize net benefit.