Interactions between Germline and Somatic Mutated Genes in Aggressive Prostate Cancer

Figure 2

Venn diagram showing differentially and nondifferentially expressed germline and somatic mutated and nonmutated genes. Middle intersections show 61 genes containing both germline and somatic mutations and are also significantly expressed with RNA-seq dataset. Germline indicates genes with germline genetic susceptibility variants from GWAS. Somatic indicates genes with somatic mutations from TCGA. RNA-seq indicates differentially expressed genes evaluated using TCGA gene expression data.