Research Article

Incidence of Skeletal-Related Events in Patients with Castration-Resistant Prostate Cancer: An Observational Retrospective Cohort Study in the US

Table 1

Demographic and clinical characteristics of the study cohort (N = 2,234).

VariableNumber of Patients (%)

Race
 White1,867 (83.6)
 Black218 (9.8)
 Asian46 (2.1)
 Hispanic48 (2.1)
 Other or 55 (2.5)
Age at cohort entry, years
 Mean (SD)76.6 (6.2)
 Distribution
  65-69297 (13.3)
  70-74625 (28.0)
  75-79595 (26.6)
  80-84451 (20.2)
  85+266 (11.9)
SRE prior to cohort 1,252 (56.0)
Use of bone-targeted agent
 First use of bone-targeted agent prior to cohort 1,213 (54.3)
 First use of bone-targeted agent after cohort entry326 (14.6)
 No use of bone-targeted agents695 (31.1)
Length of follow-up, months
 Mean (SD)10.6 (11.6)
 Distribution
  < 6 months960 (43.0)
  6 months to 1 year590 (26.4)
  > 1 to 1.5 years317 (14.2)
  > 1.5 to 2 years152 (6.8)
  > 2 years215 (9.6)

SD = standard deviation.
Categories were combined to avoid reporting a count of < 11.
Identified in the Medicare Provider Analysis and Review file, carrier claims, or outpatient claims anytime between the initial date of prostate cancer diagnosis and the cohort entry date.
Identified any time between the initial date of prostate cancer diagnosis and the cohort entry date.