Incidence of Skeletal-Related Events in Patients with Castration-Resistant Prostate Cancer: An Observational Retrospective Cohort Study in the US

Table 5

Incidence of SREs stratified by duration of androgen deprivation therapy before cohort entry.

Duration of ADT	Cases	Person-Months	Incidence Rate per 100; Person-Months (95% CI)
0 to 1 years	240	4,947	4.85 (4.26-5.51)
>1 to 2 years	245	5,976	4.10 (3.60-4.65)
>2 to 3 years	143	4,306	3.32 (2.80-3.91)
>3 to 5 years	146	4,560	3.20 (2.70-3.77)
>5 years	122	3,928	3.11 (2.58-3.71)

CI = confidence interval; SRE = skeletal-related event; ADT = androgen deprivation therapy.
Note. Cases identified using Medicare Provider Analysis and Review file, Carrier claims (Physician/Supplier Part B), and Outpatient claims.
as the interval from date of surgical castration or starting date of medical androgen deprivation therapy to date of cohort entry.