Research Article

Interleukin-10 Induces Expression of Neuroendocrine Markers and PDL1 in Prostate Cancer Cells

Table 1

Summary of NSE, SYP, and PDL1 expression in PCa cells treated with IL10, IL6, and ENZ. “++,” “+,” “+/-” indicate very strong, strong, and moderate expression, respectively, as compared to the untreated cells. “−” indicates no significant expression as compared to the untreated cells.

Cell lineNSE expressionSYP expressionPDL1 expression
IL10IL6ENZIL10IL6ENZIL10IL6ENZ

LNCaP++++++++
16DCRPC+++++++++
42DENZR+/−+/−+/−+/−+/−+/−++/−+