Somatic Mitochondrial DNA Point Mutations Used as Biomarkers to Demonstrate Genomic Heterogeneity in Primary Prostate Cancer

Figure 1

Electropherograms and peak separation as a result of cycling temperature capillary electrophoresis from initial tumor scan analysis. (a) Two samples representing the same prostate specimen, both demonstrating detected mtDNA mutations in prostate tumor 1. (b)Two samples representing the same prostate specimen, one of which demonstrating detected mtDNA mutations in prostate tumor 4.

(a)

(b)