Research Article
Relevance of Interleukins 6 and 8 Single Nucleotide Polymorphisms in Prostate Cancer: A Multicenter Study
Table 6
Relation between PSA ratio with IL-6 rs1800795 and IL-8 rs2227306 in each patient group.
| | | N | Min.–Max. | PSA ratio % Mean ± SD | Median | H | |
| Cancer group | IL-6 rs1800795 | CC | 8 | 28.8–57.5 | 36.5 ± 8.8 | 35 | 2.089 | 0.352 | CG | 14 | 27.2–46.9 | 35.1 ± 6.9 | 31.7 | GG | 18 | 29.1–56.6 | 38.7 ± 7.3 | 37.6 | IL-8 rs2227306 | CC | 12 | 27.3–47.4 | 35.5 ± 7.3 | 33.6 | 1.262 | 0.532 | CT | 17 | 29.1–57.5 | 37.6 ± 8.4 | 36 | TT | 11 | 27.2–46.9 | 37.6 ± 6.3 | 40 | Haplotypes of IL-6 rs1800795 and IL-8 rs2227306 | CC | 17 | 27.3–57.5 | 35.1 ± 7.7 | 32.5 | 2.873 | 0.412 | CT | 13 | 27.2–57.5 | 36.8 ± 8 | 35 | GC | 24 | 27.3–56.6 | 37.2 ± 7.8 | 35.5 | GT | 26 | 27.2–56.6 | 38.1 ± 6.8 | 40 |
| BPH group | IL-6 rs1800795 | CC | 9 | 15.8–24 | 18.2 ± 2.7 | 17.2 | 0.578 | 0.749 | CG | 25 | 10.5–22.4 | 17.6 ± 3.5 | 17.2 | GG | 6 | 10.5–21 | 16.4 ± 4.2 | 17.7 | IL-8 rs2227306 | CC | 3 | 10.5–16.5 | 14.3 ± 3.3 | 16 | 2.726 | 0.256 | CT | 24 | 10.5–24 | 17.7 ± 3.5 | 17.2 | TT | 13 | 12.1–22.4 | 18 ± 3.2 | 19.2 | Haplotypes of IL-6 rs1800795 and IL-8 rs2227306 | CC | 26 | 10.5–24 | 17.6 ± 3.4 | 17.2 | 4.502 | 0.212 | CT | 17 | 12.5–24 | 18.3 ± 2.9 | 19.2 | GC | 4 | 10.5–16.5 | 13.5 ± 3.5 | 13.5 | GT | 33 | 10.5–22.4 | 17.6 ± 3.5 | 18.8 |
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H: Kruskal–Wallis test, : value for association between different categories. |