Research Article

Optimal PSA Threshold for Obtaining MRI-Fusion Biopsy in Biopsy-Naïve Patients

Table 1

Clinicopathologic characteristics of the cohort.

Characteristics-continuousMean (SD)
Age (years)64.5 (7.4)
MRI prostate volume (grams)53.2 (24.5)

Median (IQR)
PSA (ng/mL)6.5 (4.8–8.6)

Characteristics-categoricalNo.%
Race/ethnicity
White23991.9
Black135.0
Hispanic31.5
Asian/Pacific Islander11.6

Location of lesions
Peripheral12748.8
Transitional6223.8
Peripheral + transitional4818.5
Central114.2
AFS20.8
Peripheral + central83.1
Peripheral + AFS10.4
Transitional + central10.4

MRI number of lesions
114756.5
27428.5
33111.9
483.1

Highest PI-RADS score
210.4
37729.6
410941.9
57328.1

MRI EPE
No22486.2
Yes3613.8

MRI SVI
No25296.9
Yes83.1

Highest Gleason group on fusion
010138.8
193.5
27729.6
3249.2
4145.4
53513.5

Highest Gleason group on standard
011042.3
12610.0
26123.5
3218.1
4155.8
52710.4

SD = standard deviation; IQR = interquartile range; ng = nanograms; mL = milliliter; MRI = magnetic resonance imaging; PSA = prostate-specific antigen; PSAV = prostate-specific antigen velocity; AFS = anterior fibromuscular stroma; PI-RADS = Prostate Imaging Reporting and Data System; EPE = extraprostatic extension; SVI = seminal vesicle invasion.