Research Article
Optimal PSA Threshold for Obtaining MRI-Fusion Biopsy in Biopsy-Naïve Patients
Table 1
Clinicopathologic characteristics of the cohort.
| Characteristics-continuous | Mean (SD) | | Age (years) | 64.5 (7.4) | | MRI prostate volume (grams) | 53.2 (24.5) | |
| | Median (IQR) | | PSA (ng/mL) | 6.5 (4.8–8.6) | |
| Characteristics-categorical | No. | % | Race/ethnicity | White | 239 | 91.9 | Black | 13 | 5.0 | Hispanic | 3 | 1.5 | Asian/Pacific Islander | 1 | 1.6 |
| Location of lesions | Peripheral | 127 | 48.8 | Transitional | 62 | 23.8 | Peripheral + transitional | 48 | 18.5 | Central | 11 | 4.2 | AFS | 2 | 0.8 | Peripheral + central | 8 | 3.1 | Peripheral + AFS | 1 | 0.4 | Transitional + central | 1 | 0.4 |
| MRI number of lesions | 1 | 147 | 56.5 | 2 | 74 | 28.5 | 3 | 31 | 11.9 | 4 | 8 | 3.1 |
| Highest PI-RADS score | 2 | 1 | 0.4 | 3 | 77 | 29.6 | 4 | 109 | 41.9 | 5 | 73 | 28.1 |
| MRI EPE | No | 224 | 86.2 | Yes | 36 | 13.8 |
| MRI SVI | No | 252 | 96.9 | Yes | 8 | 3.1 |
| Highest Gleason group on fusion | 0 | 101 | 38.8 | 1 | 9 | 3.5 | 2 | 77 | 29.6 | 3 | 24 | 9.2 | 4 | 14 | 5.4 | 5 | 35 | 13.5 |
| Highest Gleason group on standard | 0 | 110 | 42.3 | 1 | 26 | 10.0 | 2 | 61 | 23.5 | 3 | 21 | 8.1 | 4 | 15 | 5.8 | 5 | 27 | 10.4 |
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SD = standard deviation; IQR = interquartile range; ng = nanograms; mL = milliliter; MRI = magnetic resonance imaging; PSA = prostate-specific antigen; PSAV = prostate-specific antigen velocity; AFS = anterior fibromuscular stroma; PI-RADS = Prostate Imaging Reporting and Data System; EPE = extraprostatic extension; SVI = seminal vesicle invasion.
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