Research Article

The Weight of HLA-DPA1 rs3077 Single Nucleotide Polymorphism in Prostate Cancer, a Multicenter Study

Table 2

Comparison between the two studied groups according to different genotypes.

CancerControl®χ2 (p)OR (95% CI)
ObservedExpectedObservedExpected

HLA-DP rs077A(n = 40)(n = 40)
 GG17 (42.5%)19.69 (22.5%)11.66.031 (MCp = 0.049)0.0592.546 (0.964–6.726)
 AG22 (55%)16.825 (62.5%)19.90.4960.733 (0.300–1.791)
 AA1 (2.5%)3.66 (15%)8.60.0810.145 (0.017–1.268)
HWE0.0500.104
Allele frequency(n = 80)(n = 80)
 G56 (70%)43 (53.8%)4.478 (0.034)0.0352.008 (1.049–3.844)
 A24 (30%)37 (46.3%)0.0350.498 (0.260–0.954)

OR, odds ratio; CI, confidence interval; LL, lower limit; UL, upper limit; ®, reference group; χ2, chi-square test; MC, Monte Carlo; HWE, value for Hardy-Weinberg. If , not consistent with HWE. , value for comparing between the studied groups; , value for odds ratio (univariate regression analysis). Statistically significant at .