Implications of Regionalizing Care in the Developing World: Impact of Distance to Referral Center on Compliance to Biopsy Recommendations in a Brazilian Prostate Cancer Screening Cohort

Table 2

Association between distance and risk of noncompliance.

Model: logistic regression	Distance variable format	Distance (km)	OR	95% CI	value
Unadjusted	Continuous	—	2.81	2.48–3.19	<0.001
	Categorical relative to 0–249 km	250–499	2.00	1.40–2.85	<0.001
		500–999	5.88	4.07–8.51
		≥1000	15.98	11.41–22.38
Multivariable	Continuous	—	2.71	2.37–3.09	<0.001
	Categorical relative to 0–249 km	250–499	1.87	1.30–2.70	<0.001
		500–999	5.36	3.65–7.87
		≥1000	14.91	10.45–21.28

Multivariable analysis adjusted for age, log PSA, education, family history of cancer, family history of PC, DRE, and screening year. CI: confidence interval; km: kilometers; OR: odds ratio.