MRI-Based Radiotherapy Planning to Reduce Rectal Dose in Excess of Tolerance
Table 1
Rectal volume exposed to high dose radiation.
CT
MRI
value
Rx to prostate only
Median cc (IQR)
V70
9.3 (7.0, 10.2)
4.9 (4.1, 7.8)
2.1 (0.5, 5.3)
<0.001
V75
7.2 (5.6, 8.0)
3.8 (3.1, 5.7)
1.6 (0.7, 4.1)
<0.001
V80
4.0 (3.0, 4.8)
2.1 (1.5, 3.2)
0.9 (0.3, 2.6)
<0.001
Rx to prostate+1 cm SVs
Median cc (IQR)
V70
10.9 (9.4, 11.6)
6.7 (5.4, 9.3)
2.7 (0.4, 5.2)
0.007
V75
8.5 (7.0, 9.1)
4.7 (4.1, 7.0)
1.7 (−0.1, 4.3)
0.005
V80
4.6 (3.7, 5.8)
2.7 (2.2, 4.3)
0.9 (0.2, 3.0)
0.003
V70, volume of organ that receives 70 Gy or higher; V75, volume of organ that receives 75 Gy or higher; V80, volume of organ that receives 80 Gy or higher; IQR, interquartile range; cc, cubic centimeters.