Effects of SR141716A on Cognitive and Depression-Related Behavior in an Animal Model of Premotor Parkinson's Disease

Figure 2

Effects of acute administration of SR141716A (0.5 and 1 mg/kg) i.p. 30 minutes before social recognition test on 6-OHDA-treated rats. Results are expressed as mean investigation time ± SEM in comparison to sham controls. Statistical analysis was performed by two-way repeated-measure ANOVA followed by Bonferroni’s post hoc test. *P ≤  .05 compared to the first juvenile presentation (𝑛 = 8 per group).