Spinal Cord Pathology in Alpha-Synuclein Transgenic Mice

Figure 3

Mitochondrial ultrastructure in the spinal cord of 8 m-old BAsyn/PaKO. Exemplary ultrastructural features of neurons, astrocytes, and oligodendrocytes are shown for LM ((a)–(c)) and BAsyn/PaKO ((d)–(f)). Higher magnifications show examples of healthy or damaged mitochondria. Scale bars: (a)–(f): 2 𝜇m; higher magnification of (a)–(f): 0.5 𝜇m. The quantification of mitochondrial alterations is shown in (g), 𝑛=3, errors bars = SD, 𝑈-test, ^∗𝑃<.05.

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(g)