Pramipexole Extended Release: A Novel Treatment Option in Parkinson's Disease

Figure 3

simulated concentration time profile of pramipexole ER and pramipexole IR at steady state in Parkinson patients after intake of pramipexole ER 4.5 mg q.d. or pramipexole t.i.d.) in intervals of 8 hours (8-8-8) or different intervals of 6 and 12 hours (6-6-12) [9].