Total Cholesterol and the Risk of Parkinson's Disease: A Review for Some New Findings
Table 2
Hazard ratio (HR) of Parkinson disease according to different levels of total cholesterol among various subpopulations [16]*.
HR (95% CI)
Total cholesterol (mmol/L)
for trend
5
5–5.9
6–6.9
7.0
Total samples
1.00
1.42 (1.00–2.03)
1.56 (1.10–2.21)
1.86 (1.31–2.63)
.002
Gender
Men
1.00
1.33 (0.81–2.16)
1.53 (0.96–2.46)
1.84 (1.14–2.95)
.035
Women
1.00
1.55 (0.92–2.61)
1.57 (0.93–2.64)
1.86 (1.11–3.13)
.113
Age (years)
25–44
1.00
1.90 (1.05–3.45)
1.79 (0.97–3.30)
2.54 (1.37–4.70)
.025
45–54
1.00
1.34 (0.67–2.67)
1.65 (0.85–3.20)
2.20 (1.14–4.24)
.011
55–74
1.00
1.00 (0.56–1.79)
1.07 (0.61–1.88)
1.03 (0.59–1.81)
.98
Smoking
Never
1.00
1.34 (0.85–2.12)
1.57 (1.01–2.45)
1.74 (1.11–2.71)
.061
Ever or current
1.00
1.58 (0.89–2.79)
1.55 (0.88–2.72)
2.05 (1.18–3.59)
.044
djusted for age, sex (exception in gender analyses), study year, body mass index, systolic blood pressure, education, leisure-time physical activity, smoking (except in smoking status analysis), coffee, tea, and alcohol consumption, cholesterol-lowering agent use, and history of diabetes.
